- Human cleft lip and palate fibroblasts and normal nicotine-treated fibroblasts show altered in vitro expressions of genes related to molecular signaling pathways and extracellular matrix metabolism. Baroni, T., Bellucci, C., Lilli, C., Pezzetti, F., Carinci, F., Lumare, E., Palmieri, A., Stabellini, G., Bodo, M. J. Cell. Physiol. (2010)