- Monoclonal antibodies specific for beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) reduce inflammation in the colon of scid mice reconstituted with CD45RBhigh CD4+ T cells. Picarella, D., Hurlbut, P., Rottman, J., Shi, X., Butcher, E., Ringler, D.J. J. Immunol. (1997)