The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Lymphoid Tissue

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Lymphoid Tissue


Psychiatry related information on Lymphoid Tissue


High impact information on Lymphoid Tissue

  • Studies over the past few years have identified lymphotoxin as a critical signaling molecule not only for the organogenesis of secondary lymphoid tissues but for the maintenance of aspects of their microarchitecture as well [6].
  • Furthermore, antigen that stimulates the gut-associated lymphoid tissue preferentially generates a Th2 type response [7].
  • RelB, a member of the NF-kappa B/Rel family of transcription factors, has been implicated in the constitutive expression of kappa B-regulated genes in lymphoid tissues [8].
  • Transcripts of the human gene, for which we propose the name TAN-1, and its murine counterpart are present in many normal human fetal and adult mouse tissues, but are most abundant in lymphoid tissues [9].
  • Moreover, peripheral lymphoid tissues of younger mice were markedly (as much as 100-fold) more immunoreactive (both Con A response and alloreactivity) [10].

Chemical compound and disease context of Lymphoid Tissue


Biological context of Lymphoid Tissue


Anatomical context of Lymphoid Tissue


Associations of Lymphoid Tissue with chemical compounds


Gene context of Lymphoid Tissue


Analytical, diagnostic and therapeutic context of Lymphoid Tissue


  1. Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Brown, K.L., Stewart, K., Ritchie, D.L., Mabbott, N.A., Williams, A., Fraser, H., Morrison, W.I., Bruce, M.E. Nat. Med. (1999) [Pubmed]
  2. Suppression of CCR5- but not CXCR4-tropic HIV-1 in lymphoid tissue by human herpesvirus 6. Grivel, J.C., Ito, Y., Fagà, G., Santoro, F., Shaheen, F., Malnati, M.S., Fitzgerald, W., Lusso, P., Margolis, L. Nat. Med. (2001) [Pubmed]
  3. Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity. Bende, R.J., Aarts, W.M., Riedl, R.G., de Jong, D., Pals, S.T., van Noesel, C.J. J. Exp. Med. (2005) [Pubmed]
  4. Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. Stenger, S., Donhauser, N., Thüring, H., Röllinghoff, M., Bogdan, C. J. Exp. Med. (1996) [Pubmed]
  5. Blockade of CC chemokine receptor 5 (CCR5)-tropic human immunodeficiency virus-1 replication in human lymphoid tissue by CC chemokines. Margolis, L.B., Glushakova, S., Grivel, J.C., Murphy, P.M. J. Clin. Invest. (1998) [Pubmed]
  6. Development and maturation of secondary lymphoid tissues. Fu, Y.X., Chaplin, D.D. Annu. Rev. Immunol. (1999) [Pubmed]
  7. Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Weiner, H.L., Friedman, A., Miller, A., Khoury, S.J., al-Sabbagh, A., Santos, L., Sayegh, M., Nussenblatt, R.B., Trentham, D.E., Hafler, D.A. Annu. Rev. Immunol. (1994) [Pubmed]
  8. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family. Weih, F., Carrasco, D., Durham, S.K., Barton, D.S., Rizzo, C.A., Ryseck, R.P., Lira, S.A., Bravo, R. Cell (1995) [Pubmed]
  9. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Ellisen, L.W., Bird, J., West, D.C., Soreng, A.L., Reynolds, T.C., Smith, S.D., Sklar, J. Cell (1991) [Pubmed]
  10. T cell function and expression are dramatically altered in T cell receptor V gamma 1.1J gamma 4C gamma 4 transgenic mice. Ferrick, D.A., Sambhara, S.R., Ballhausen, W., Iwamoto, A., Pircher, H., Walker, C.L., Yokoyama, W.M., Miller, R.G., Mak, T.W. Cell (1989) [Pubmed]
  11. 2-Chlorodeoxyadenosine as first-line treatment in bronchus-associated lymphoid tissue lymphoma. Neumeister, P., Linkesch, W., Höfler, G., Sill, H. Blood (1996) [Pubmed]
  12. Influence of adrenal corticosteroids on the susceptibility of cats to feline leukemia virus infection. Rojko, J.L., Hoover, E.A., Mathes, L.E., Krakowka, S., Olsen, R.G. Cancer Res. (1979) [Pubmed]
  13. Tumor necrosis factor receptors in lymphoid tissues and lymphomas. Source and site of action of tumor necrosis factor alpha. Ryffel, B., Brockhaus, M., Dürmüller, U., Gudat, F. Am. J. Pathol. (1991) [Pubmed]
  14. Decrease of HIV-1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine. Ritonavir/3TC/ZDV Study Group. Notermans, D.W., Jurriaans, S., de Wolf, F., Foudraine, N.A., de Jong, J.J., Cavert, W., Schuwirth, C.M., Kauffmann, R.H., Meenhorst, P.L., McDade, H., Goodwin, C., Leonard, J.M., Goudsmit, J., Danner, S.A. AIDS (1998) [Pubmed]
  15. Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years. Günthard, H.F., Havlir, D.V., Fiscus, S., Zhang, Z.Q., Eron, J., Mellors, J., Gulick, R., Frost, S.D., Brown, A.J., Schleif, W., Valentine, F., Jonas, L., Meibohm, A., Ignacio, C.C., Isaacs, R., Gamagami, R., Emini, E., Haase, A., Richman, D.D., Wong, J.K. J. Infect. Dis. (2001) [Pubmed]
  16. Inhibition of death receptor signals by cellular FLIP. Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J.L., Schröter, M., Burns, K., Mattmann, C., Rimoldi, D., French, L.E., Tschopp, J. Nature (1997) [Pubmed]
  17. Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. Yin, L., Wu, L., Wesche, H., Arthur, C.D., White, J.M., Goeddel, D.V., Schreiber, R.D. Science (2001) [Pubmed]
  18. T cell-mediated elimination of B7.2 transgenic B cells. Fournier, S., Rathmell, J.C., Goodnow, C.C., Allison, J.P. Immunity (1997) [Pubmed]
  19. Virus-specific CD8 T cells in peripheral tissues are more resistant to apoptosis than those in lymphoid organs. Wang, X.Z., Stepp, S.E., Brehm, M.A., Chen, H.D., Selin, L.K., Welsh, R.M. Immunity (2003) [Pubmed]
  20. BCL8, a novel gene involved in translocations affecting band 15q11-13 in diffuse large-cell lymphoma. Dyomin, V.G., Rao, P.H., Dalla-Favera, R., Chaganti, R.S. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  21. NF-AT components define a family of transcription factors targeted in T-cell activation. Northrop, J.P., Ho, S.N., Chen, L., Thomas, D.J., Timmerman, L.A., Nolan, G.P., Admon, A., Crabtree, G.R. Nature (1994) [Pubmed]
  22. The CDM protein DOCK2 in lymphocyte migration. Reif, K., Cyster, J. Trends Cell Biol. (2002) [Pubmed]
  23. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Arbonés, M.L., Ord, D.C., Ley, K., Ratech, H., Maynard-Curry, C., Otten, G., Capon, D.J., Tedder, T.F. Immunity (1994) [Pubmed]
  24. Regional blood flow and its relationship to lymphocyte and lymphoblast traffic during a primary immune reaction. Ottaway, C.A., Parrott, D.M. J. Exp. Med. (1979) [Pubmed]
  25. The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues. Wu, Q., Wang, Y., Wang, J., Hedgeman, E.O., Browning, J.L., Fu, Y.X. J. Exp. Med. (1999) [Pubmed]
  26. Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Mabbott, N.A., Bruce, M.E., Botto, M., Walport, M.J., Pepys, M.B. Nat. Med. (2001) [Pubmed]
  27. Schlafen, a new family of growth regulatory genes that affect thymocyte development. Schwarz, D.A., Katayama, C.D., Hedrick, S.M. Immunity (1998) [Pubmed]
  28. Lymphocyte homing to bronchus-associated lymphoid tissue (BALT) is mediated by L-selectin/PNAd, alpha4beta1 integrin/VCAM-1, and LFA-1 adhesion pathways. Xu, B., Wagner, N., Pham, L.N., Magno, V., Shan, Z., Butcher, E.C., Michie, S.A. J. Exp. Med. (2003) [Pubmed]
  29. Demonstration of large-scale migration of cortical thymocytes to peripheral lymphoid tissues in cyclosporin A-treated rats. Zadeh, H.H., Goldschneider, I. J. Exp. Med. (1993) [Pubmed]
  30. CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720. Henning, G., Ohl, L., Junt, T., Reiterer, P., Brinkmann, V., Nakano, H., Hohenberger, W., Lipp, M., Förster, R. J. Exp. Med. (2001) [Pubmed]
  31. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Fütterer, A., Mink, K., Luz, A., Kosco-Vilbois, M.H., Pfeffer, K. Immunity (1998) [Pubmed]
  32. Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production. Kang, H.S., Chin, R.K., Wang, Y., Yu, P., Wang, J., Newell, K.A., Fu, Y.X. Nat. Immunol. (2002) [Pubmed]
  33. B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. Legler, D.F., Loetscher, M., Roos, R.S., Clark-Lewis, I., Baggiolini, M., Moser, B. J. Exp. Med. (1998) [Pubmed]
  34. A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: genetic evidence of synergism with lymphotoxin beta. Koni, P.A., Flavell, R.A. J. Exp. Med. (1998) [Pubmed]
  35. Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells. Ehrhardt, G.R., Hsu, J.T., Gartland, L., Leu, C.M., Zhang, S., Davis, R.S., Cooper, M.D. J. Exp. Med. (2005) [Pubmed]
  36. Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor. Lu, L., Rudert, W.A., Qian, S., McCaslin, D., Fu, F., Rao, A.S., Trucco, M., Fung, J.J., Starzl, T.E., Thomson, A.W. J. Exp. Med. (1995) [Pubmed]
  37. Stages of B cell differentiation in human lymphoid tissue. Bhan, A.K., Nadler, L.M., Stashenko, P., McCluskey, R.T., Schlossman, S.F. J. Exp. Med. (1981) [Pubmed]
  38. In vivo analysis of Fas/FasL interactions in HIV-infected patients. Badley, A.D., Dockrell, D.H., Algeciras, A., Ziesmer, S., Landay, A., Lederman, M.M., Connick, E., Kessler, H., Kuritzkes, D., Lynch, D.H., Roche, P., Yagita, H., Paya, C.V. J. Clin. Invest. (1998) [Pubmed]
  39. Cloning and expression of human deoxyguanosine kinase cDNA. Johansson, M., Karlsson, A. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  40. Rapid, nonradioactive detection of clonal T-cell receptor gene rearrangements in lymphoid neoplasms. Bourguin, A., Tung, R., Galili, N., Sklar, J. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
WikiGenes - Universities