Disease relevance of Arsenic III

• The interactions of an arsenic (III) reagent, (CH3)2AsSCH2CONH2, with two Escherichia coli RI methyltransferase mutants, W183F and C223S, have been studied by phosphorescence, optically detected magnetic resonance, and fluorescence spectroscopy [1].

High impact information on Arsenic III

• Previous studies in our laboratory demonstrated that effects of low-dose arsenic (III) (arsenite) on expression of the hormone-regulated phosphoenolpyruvate carboxykinase (PEPCK) gene were strongly associated with the glucocorticoid receptor (GR)-mediated regulatory pathway [2].
• Pre-incubation of cells with inorganic arsenic (III) further induced antimony methylation capability, whereas pre-incubation with inorganic antimony (III) did not [3].
• Toxic effects of arsenic (III) on some hematopoietic and central nervous system variables in rats and guinea pigs [4].
• The hepatic delta-aminolevulinic acid dehydratase and delta-aminolevulinic acid synthetase activity increased in chronic arsenic (III) exposure in rats and guinea pigs [4].
• Effect of long-term administration of arsenic (III) and bromine with and without selenium and iodine supplementation on the element level in the thyroid of rat [5].

Gene context of Arsenic III

• Arsenic (III) administration markedly increased the activities of ALT and ALP in the liver and kidneys [6].

Analytical, diagnostic and therapeutic context of Arsenic III

• Oxidation and removal of arsenic (III) from aerated groundwater by filtration through sand and zero-valent iron [7].
• METHODS AND RESULTS: A culture of Microbacterium lacticum oxidizing up to 50 mmol l(-1) arsenic (III) was isolated from municipal sewage by an enrichment culture technique [8].

References