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Chemical Compound Review:

CHEMBL46422 1,2,3,4-tetrachlorobenzene

Synonyms: SureCN348089, CCRIS 5935, AG-G-35689, ACMC-209nfu, CHEBI:18855, ...

Kitchin, K.T. et al., Ahn, Y.B. et al., Kimball, B.A. et al., Inoue, K. et al., Leslie, H.A. et al.

Leslie, Kraak, Hermens,

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Disease relevance of NSC50729

Chronic toxicity and body residues of the nonpolar narcotic 1,2,3,4-tetrachlorobenzene in Chironomus riparius [1].

High impact information on NSC50729

Fundamental adsorption characteristics of carbonaceous adsorbents for 1,2,3,4-tetrachlorobenzene in a model gas of an incineration plant [2].
The most effective stimulation of 1,2,3,4-TeCDD dechlorination occurred with coamendment of 25 microM of 1,2,3,4-tetrachlorobenzene (TeCB), 2,3,4,5-tetrachloroanisole (TeCA), 2,3,4,5-tetrachlorophenol, or 2',3',4'-trichloroacetophenone plus 500 microM lactate and 500 microM propionate as electron donors [3].
To assess possible maternal hepatic and reproductive effects of this uncharged, low molecular weight, lipophilic chlorinated benzene 0, 100, 300 and 1000 mg/kg/day of 1,2,3,4-tetrachlorobenzene (TCB) was orally administered to pregnant rats on days 9-13 of gestation and the animals were killed on day 14 of pregnancy [4].
Pentachlorobenzene (PeCB) and 1,2,3,4-tetrachlorobenzene (TeCB) were evaluated as oral chemical biomarkers when administered to coyotes (Canis latrans) during the period of 31 January to 10 August 1994 [5].

References

Chronic toxicity and body residues of the nonpolar narcotic 1,2,3,4-tetrachlorobenzene in Chironomus riparius. Leslie, H.A., Kraak, M.H., Hermens, J.L. Environ. Toxicol. Chem. (2004) [Pubmed]
Fundamental adsorption characteristics of carbonaceous adsorbents for 1,2,3,4-tetrachlorobenzene in a model gas of an incineration plant. Inoue, K., Kawamoto, K. Environ. Sci. Technol. (2005) [Pubmed]
Co-amendment with halogenated compounds enhances anaerobic microbial dechlorination of 1,2,3,4-tetrachlorodibenzo-P-dioxin and 1,2,3,4-tetrachlorodibenzofuran in estuarine sediments. Ahn, Y.B., Häggblom, M.M., Fennell, D.E. Environ. Toxicol. Chem. (2005) [Pubmed]
Maternal hepatic and embryonic effects of 1,2,3,4-tetrachlorobenzene in the rat. Kitchin, K.T., Ebron, M.T. Toxicology (1983) [Pubmed]
Two new oral chemical biomarkers for coyotes. Kimball, B.A., Windberg, L.A., Furcolow, C.A., Roetto, M., Johnston, J.J. J. Wildl. Dis. (1996) [Pubmed]

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