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Chemical Compound Review

PubChem3718     1,2,4,5-tetrachlorobenzene

Synonyms: CCRIS 766, CHEMBL45428, SureCN348913, ACMC-209s62, CHEBI:36697, ...
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Disease relevance of NSC27003


High impact information on NSC27003


Chemical compound and disease context of NSC27003


Biological context of NSC27003


Anatomical context of NSC27003


Associations of NSC27003 with other chemical compounds

  • Residues of PeCB were detected in serum, feces, and adipose and muscle tissues for 120 days post-treatment; TeCB residues were detected in feces and serum at 1 and 8 days post-treatment and in adipose tissue at 30 days post-treatment [16].

Analytical, diagnostic and therapeutic context of NSC27003


  1. Transformation of chlorinated benzenes and toluenes by Ralstonia sp. strain PS12 tecA (tetrachlorobenzene dioxygenase) and tecB (chlorobenzene dihydrodiol dehydrogenase) gene products. Pollmann, K., Beil, S., Pieper, D.H. Appl. Environ. Microbiol. (2001) [Pubmed]
  2. Identification of chlorobenzene dioxygenase sequence elements involved in dechlorination of 1,2,4,5-tetrachlorobenzene. Beil, S., Mason, J.R., Timmis, K.N., Pieper, D.H. J. Bacteriol. (1998) [Pubmed]
  3. Degradation of alkanes and highly chlorinated benzenes, and production of biosurfactants, by a psychrophilic Rhodococcus sp. and genetic characterization of its chlorobenzene dioxygenase. Rapp, P., Gabriel-Jürgens, L.H. Microbiology (Reading, Engl.) (2003) [Pubmed]
  4. Genetic and biochemical characterization of the broad spectrum chlorobenzene dioxygenase from Burkholderia sp. strain PS12--dechlorination of 1,2,4,5-tetrachlorobenzene. Beil, S., Happe, B., Timmis, K.N., Pieper, D.H. Eur. J. Biochem. (1997) [Pubmed]
  5. The acute and chronic toxicity of ten chlorinated organic compounds to the American flagfish (Jordanella floridae). Smith, A.D., Bharath, A., Mallard, C., Orr, D., Smith, K., Sutton, J.A., Vukmanich, J., McCarty, L.S., Ozburn, G.W. Arch. Environ. Contam. Toxicol. (1991) [Pubmed]
  6. The boron-catalyzed polymerization of dimethylsulfoxonium methylide. A living polymethylene synthesis. Busch, B.B., Paz, M.M., Shea, K.J., Staiger, C.L., Stoddard, J.M., Walker, J.R., Zhou, X.Z., Zhu, H. J. Am. Chem. Soc. (2002) [Pubmed]
  7. Carcinogenicity of by-products of disinfection in mouse and rat liver. Herren-Freund, S.L., Pereira, M.A. Environ. Health Perspect. (1986) [Pubmed]
  8. Stochastic simulation of hepatic preneoplastic foci development for four chlorobenzene congeners in a medium-term bioassay. Ou, Y.C., Conolly, R.B., Thomas, R.S., Gustafson, D.L., Long, M.E., Dobrev, I.D., Chubb, L.S., Xu, Y., Lapidot, S.A., Andersen, M.E., Yang, R.S. Toxicol. Sci. (2003) [Pubmed]
  9. Cation-pi bonding: a new perspective on the sorption of polycyclic aromatic hydrocarbons to mineral surfaces. Zhu, D., Herbert, B.E., Schlautman, M.A., Carraway, E.R., Hur, J. J. Environ. Qual. (2004) [Pubmed]
  10. Toxicokinetics of aromatic amines in guppy, Poecilia reticulata. de Wolf, W., Yedema, E., Seinen, W., Hermens, J.L. Sci. Total Environ. (1991) [Pubmed]
  11. Effect of phenobarbital and polychlorinated biphenyls on the toxicity and disposition of 1,2,4,5-tetrachlorobenzene in the rat. Chu, I., Villeneuve, D.C., Yagminas, A., Valli, V.E. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. (1986) [Pubmed]
  12. A teratological evaluation and analysis of fetal tissue levels following administration of tetrachlorobenzene isomers to the rat. Kacew, S., Ruddick, J.A., Parulekar, M., Valli, V.E., Chu, I., Villeneuve, D.C. Teratology (1984) [Pubmed]
  13. Maternal hepatic effects of 1,2,4,5-tetrachlorobenzene in the rat. Kitchin, K.T., Ebron, M.T. Environmental research. (1983) [Pubmed]
  14. Levels and trends of chlorinated hydrocarbon contaminants in the breast milk of Canadian women. Mes, J., Davies, D.J., Turton, D., Sun, W.F. Food additives and contaminants. (1986) [Pubmed]
  15. Metabolism of 1,2,3,4-, 1,2,3,5-, and 1,2,4,5-tetrachlorobenzene in the rat. Chu, I., Villeneuve, D.C., Viau, A., Barnes, C.R., Benoit, F.M., Qin, Y.H. Journal of toxicology and environmental health. (1984) [Pubmed]
  16. Two new oral chemical biomarkers for coyotes. Kimball, B.A., Windberg, L.A., Furcolow, C.A., Roetto, M., Johnston, J.J. J. Wildl. Dis. (1996) [Pubmed]
  17. Single-crystal X-ray and neutron powder diffraction investigation of the phase transition in tetrachlorobenzene. Barnett, S.A., Broder, C.K., Shankland, K., David, W.I., Ibberson, R.M., Tocher, D.A. Acta Crystallogr., B (2006) [Pubmed]
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