Chemical Compound Review:
lactate 2-hydroxypropanoate
Synonyms:
b-lactate, AG-D-32891, CHEBI:24996, CTK4A8148, AR-1I0651, ...
This record was replaced with 612.
- Natural history of lactic acidosis after grand-mal seizures. A model for the study of an anion-gap acidosis not associated with hyperkalemia. Orringer, C.E., Eustace, J.C., Wunsch, C.D., Gardner, L.B. N. Engl. J. Med. (1977)
- Stimulation of lactate production by administration of bicarbonate in a patient with a solid neoplasm and lactic acidosis. Fraley, D.S., Adler, S., Bruns, F.J., Zett, B. N. Engl. J. Med. (1980)
- Elevated blood cyanide concentrations in victims of smoke inhalation. Baud, F.J., Barriot, P., Toffis, V., Riou, B., Vicaut, E., Lecarpentier, Y., Bourdon, R., Astier, A., Bismuth, C. N. Engl. J. Med. (1991)
- Angina due to coronary microvascular disease in hypertensive patients without left ventricular hypertrophy. Brush, J.E., Cannon, R.O., Schenke, W.H., Bonow, R.O., Leon, M.B., Maron, B.J., Epstein, S.E. N. Engl. J. Med. (1988)
- Metabolic effects of dichloroacetate in patients with diabetes mellitus and hyperlipoproteinemia. Stacpoole, P.W., Moore, G.W., Kornhauser, D.M. N. Engl. J. Med. (1978)
- A focal brain abnormality in panic disorder, a severe form of anxiety. Reiman, E.M., Raichle, M.E., Butler, F.K., Herscovitch, P., Robins, E. Nature (1984)
- Lactate provocation of panic attacks. II. Biochemical and physiological findings. Liebowitz, M.R., Gorman, J.M., Fyer, A.J., Levitt, M., Dillon, D., Levy, G., Appleby, I.L., Anderson, S., Palij, M., Davies, S.O. Arch. Gen. Psychiatry (1985)
- Altered metabolic properties of cultured skin fibroblasts in Alzheimer's disease. Sims, N.R., Finegan, J.M., Blass, J.P. Ann. Neurol. (1987)
- Energy metabolism defects in Huntington's disease and effects of coenzyme Q10. Koroshetz, W.J., Jenkins, B.G., Rosen, B.R., Beal, M.F. Ann. Neurol. (1997)
- Brain function rescue effect of lactate following hypoglycaemia is not an adaptation process in both normal and type I diabetic subjects. Maran, A., Crepaldi, C., Trupiani, S., Lucca, T., Jori, E., Macdonald, I.A., Tiengo, A., Avogaro, A., Del Prato, S. Diabetologia (2000)
- Lactate-proton cotransport in skeletal muscle. Juel, C. Physiol. Rev. (1997)
- Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation. Scheper, G.C., van der Klok, T., van Andel, R.J., van Berkel, C.G., Sissler, M., Smet, J., Muravina, T.I., Serkov, S.V., Uziel, G., Bugiani, M., Schiffmann, R., Krägeloh-Mann, I., Smeitink, J.A., Florentz, C., Van Coster, R., Pronk, J.C., van der Knaap, M.S. Nat. Genet. (2007)
- The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA. Mandel, H., Szargel, R., Labay, V., Elpeleg, O., Saada, A., Shalata, A., Anbinder, Y., Berkowitz, D., Hartman, C., Barak, M., Eriksson, S., Cohen, N. Nat. Genet. (2001)
- Anaerobic bacteria in nonspecific vaginitis. Spiegel, C.A., Amsel, R., Eschenbach, D., Schoenknecht, F., Holmes, K.K. N. Engl. J. Med. (1980)
- Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy. Huang, C.C., Wang, S.T., Chang, Y.C., Lin, K.P., Wu, P.L. N. Engl. J. Med. (1999)
- Treatment of lactic acidosis with dichloroacetate. Stacpoole, P.W., Harman, E.M., Curry, S.H., Baumgartner, T.G., Misbin, R.I. N. Engl. J. Med. (1983)
- Evidence for a detrimental effect of bicarbonate therapy in hypoxic lactic acidosis. Graf, H., Leach, W., Arieff, A.I. Science (1985)
- A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework. Wilks, H.M., Hart, K.W., Feeney, R., Dunn, C.R., Muirhead, H., Chia, W.N., Barstow, D.A., Atkinson, T., Clarke, A.R., Holbrook, J.J. Science (1988)
- Coronary bypass for stable angina: a prospective randomized study. Kloster, F.E., Kremkau, E.L., Ritzmann, L.W., Rahimtoola, S.H., Rösch, J., Kanarek, P.H. N. Engl. J. Med. (1979)
- Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. Stumvoll, M., Nurjhan, N., Perriello, G., Dailey, G., Gerich, J.E. N. Engl. J. Med. (1995)
- The acidosis of cholera. Contributions of hyperproteinemia, lactic acidemia, and hyperphosphatemia to an increased serum anion gap. Wang, F., Butler, T., Rabbani, G.H., Jones, P.K. N. Engl. J. Med. (1986)
- Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cAMP. Strickland, S., Smith, K.K., Marotti, K.R. Cell (1980)
- Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Garcia, C.K., Goldstein, J.L., Pathak, R.K., Anderson, R.G., Brown, M.S. Cell (1994)
- GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier. Seidner, G., Alvarez, M.G., Yeh, J.I., O'Driscoll, K.R., Klepper, J., Stump, T.S., Wang, D., Spinner, N.B., Birnbaum, M.J., De Vivo, D.C. Nat. Genet. (1998)
- Deficiency of protein-carboxyl methylase in immotile spermatozoa of infertile men. Gagnon, C., Sherins, R.J., Phillips, D.M., Bardin, C.W. N. Engl. J. Med. (1982)
- Diagnostic value of blood sampling in fetuses with growth retardation. Pardi, G., Cetin, I., Marconi, A.M., Lanfranchi, A., Bozzetti, P., Ferrazzi, E., Buscaglia, M., Battaglia, F.C. N. Engl. J. Med. (1993)
- Serum lactate dehydrogenase and bone marrow involvement in small-cell carcinoma of the lung. Doll, D.C. N. Engl. J. Med. (1985)
- Acute hypothalamic-pituitary-adrenal responses to the stress of treadmill exercise. Physiologic adaptations to physical training. Luger, A., Deuster, P.A., Kyle, S.B., Gallucci, W.T., Montgomery, L.C., Gold, P.W., Loriaux, D.L., Chrousos, G.P. N. Engl. J. Med. (1987)
- Increase in human skeletal muscle lactate produced by fenfluramine. Kirby, M.J., Turner, P. Nature (1976)
- Lactate-supported synaptic function in the rat hippocampal slice preparation. Schurr, A., West, C.A., Rigor, B.M. Science (1988)
- Lactate dehydrogenases of Atlantic hagfish: physiological and evolutionary implications of a primitive heart isozyme. Sidell, B.D., Beland, K.F. Science (1980)
- Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. Strassmann, G., Patil-Koota, V., Finkelman, F., Fong, M., Kambayashi, T. J. Exp. Med. (1994)
- PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium. Dupont, J., Renou, J.P., Shani, M., Hennighausen, L., LeRoith, D. J. Clin. Invest. (2002)
- The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. Yen, H.C., Oberley, T.D., Vichitbandha, S., Ho, Y.S., St Clair, D.K. J. Clin. Invest. (1996)
- Cyclin-dependent kinase inhibitor p27(Kip1) is required for mouse mammary gland morphogenesis and function. Muraoka, R.S., Lenferink, A.E., Simpson, J., Brantley, D.M., Roebuck, L.R., Yakes, F.M., Arteaga, C.L. J. Cell Biol. (2001)
- Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia. Deora, A.A., Philp, N., Hu, J., Bok, D., Rodriguez-Boulan, E. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma. Offit, K., Lo Coco, F., Louie, D.C., Parsa, N.Z., Leung, D., Portlock, C., Ye, B.H., Lista, F., Filippa, D.A., Rosenbaum, A. N. Engl. J. Med. (1994)
- Treatment of circulatory shock with dopamine. Studies on survival. Ruiz, C.E., Weil, M.H., Carlson, R.W. JAMA (1979)
- Energy expenditure with indoor exercise machines. Zeni, A.I., Hoffman, M.D., Clifford, P.S. JAMA (1996)
- 'Lactate washout' following circulatory arrest. Leavy, J.A., Weil, M.H., Rackow, E.C. JAMA (1988)
- Diagnosis and treatment of cholera in the United States. Are we prepared? Besser, R.E., Feikin, D.R., Eberhart-Phillips, J.E., Mascola, L., Griffin, P.M. JAMA (1994)