Disease relevance of p-Aminophenylmercaptan

• Thiophenol and 4-aminothiophenol were used to study levels of toxicity in human red blood cells [1].

High impact information on p-Aminophenylmercaptan

• To search for donor sites, we treated bovine thyroglobulin with 4-aminothiophenol to specifically modify dehydroalanine residues to S-(4-aminophenyl)cysteine (APC) residues, according to the principle of dehydroalanine determination developed by us (Kondo, T., Kondo, Y., and Ui, N. (1988) Mol. Cell. Endocr. 57, 101-106) [2].
• The aromatic compounds 2-aminothiophenol, 3-aminothiophenol, and 4-aminothiophenol shared with CySH the ability to inhibit PRL assayability and release, but were all more potent [3].
• Under these conditions, a portion of the 4-aminothiophenol was desulfurized to aniline with first-order kinetics and with a rate constant estimated by kinetic modeling to be 7.0 x 10-6 s-1 [4].
• The 4-aminothiophenol-labeled dehydroalanine (4-aminophenylcysteine) residues were liberated by acidic hydrolysis, converted to a colored derivative by the Bratton-Marshall reaction and quantified colorimetrically [5].
• Thyroglobulin preparations were labeled with 4-aminothiophenol at 30 degrees C for 10 days [5].

Associations of p-Aminophenylmercaptan with other chemical compounds

• Charge transfer between the adsorbed 4-aminothiophenol (PATP) and the immobilized silver nanoparticles was studied by surface-enhanced Raman spectroscopy with 1064 nm excitation, and compared with that of the silver nanoparticles in the colloid [6].
• The parent gold nanoparticles were then capped with a 4-aminothiophenol protecting layer and transferred into toluene by tuning the surface charge of the modified nanoparticles [7].

Gene context of p-Aminophenylmercaptan

• 5. Though CySH and 4-aminothiophenol induced changes in the electrophoretic migration of granule PRL, similar changes occurred in the migration of standard purified hormone despite the known absence of immunochemical effects [3].
• A theoretical analysis of recent experiments measuring the 782 nm surface-enhanced Raman scattering of p-mercaptoaniline bound to silver nanoshells of different core and shell radii [J. B. Jackson and N. J. Halas, Proc. Natl. Acad. Sci. U.S.A. 101, 17930 (2004)] is performed [8].

Analytical, diagnostic and therapeutic context of p-Aminophenylmercaptan

• The redox reactions of [Fe(CN)6](4-)/[Fe(CN)6](3-) on the gold surface were blocked due to the procedures of self-assembly of 4-aminothiophenol and antibody immobilization, which were investigated by cyclic voltammetry and impedance spectroscopy [9].
• More importantly, it was found that the multilayered NRs films could be used as a surface-enhanced Raman spectroscopy (SERS) substrate for probing 4-aminothiophenol (4-ATP) [10].

References