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Chemical Compound Review

PubChem5424     2-aminobenzenethiol

Synonyms: SureCN7807, CHEMBL116835, NSC-4738, CCRIS 9096, AG-C-90623, ...
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Disease relevance of NSC 4738


High impact information on NSC 4738


Biological context of NSC 4738

  • The complex [VO(Cl)S'NS'] (5; H(2)S'NS' is the Schiff base formed between o-mercaptoaniline and o-mercaptobenzaldehyde) is obtained by redox interaction between [VCl(3)(THF)(3)] and 2,2'-dithiodibenzaldehyde in the presence of o-mercaptoaniline.The crystal and molecular structures have been obtained for 3 [6].

Associations of NSC 4738 with other chemical compounds


Gene context of NSC 4738

  • The gold(I) thiolate complexes [Au(2-SC6H4NH2)(PPh3)] (1), [PPN][Au(2-SC6H4NH2)2] (2) (PPN = PPh3=N=PPh3), and [{Au(2-SC6H4NH2)}2(mu-dppm)] (3) (dppm = PPh2CH2PPh2) have been prepared by reaction of acetylacetonato gold(I) precursors with 2-aminobenzenethiol in the appropriate molar ratio [9].


  1. Systemic contact dermatitis after inhalation of 2-aminothiophenol. Ducatman, A.M., Bigby, M. Contact Derm. (1988) [Pubmed]
  2. Exposure-pattern dermatitis due to 2-aminothiophenol and 2-aminophenyldisulfide. Sommer, S., Wilkinson, S.M., Quinlan, R. Contact Derm. (1999) [Pubmed]
  3. Occupational airborne allergic contact dermatitis from 2-aminothiophenol. Bonamonte, D., Carino, M., Mundo, L., Foti, C. European journal of dermatology : EJD. (2002) [Pubmed]
  4. Inactivation of yeast hexokinase by 2-aminothiophenol. Evidence for a 'half-of-the-sites' mechanism. Puri, R.N., Roskoski, R. Biochem. J. (1988) [Pubmed]
  5. Cysteamine-induced decrease of somatostatin in rat brain synaptosomes in vitro. Widmann, R., Sperk, G. Endocrinology (1987) [Pubmed]
  6. Thiofunctional vanadium complexes. Nekola, H., Wang, D., Grüning, C., Gätjens, J., Behrens, A., Rehder, D. Inorganic chemistry. (2002) [Pubmed]
  7. Fluorescence assay of nitrofurantoin with o-aminothiophenol in plasma and urine. Watari, N., Funaki, T., Kaneniwa, N. Journal of pharmaceutical sciences. (1980) [Pubmed]
  8. Synthesis of carbon-11 labeled fluorinated 2-arylbenzothiazoles as novel potential PET cancer imaging agents. Wang, M., Gao, M., Mock, B.H., Miller, K.D., Sledge, G.W., Hutchins, G.D., Zheng, Q.H. Bioorg. Med. Chem. (2006) [Pubmed]
  9. Synthesis, structural characterization, and theoretical studies of gold(I) and gold(I)-gold(III) thiolate complexes: quenching of gold(I) thiolate luminescence. Bardají, M., Calhorda, M.J., Costa, P.J., Jones, P.G., Laguna, A., Reyes Pérez, M., Villacampa, M.D. Inorganic chemistry. (2006) [Pubmed]
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