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Chemical Compound Review

sodium octanoate     sodium octanoate

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Disease relevance of octanoic acid


High impact information on octanoic acid


Chemical compound and disease context of octanoic acid

  • These results indicate that sodium caprylate is effective in killing E. coli O157:H7 in cattle drinking water, but detailed cattle palatability studies of water containing caprylate are necessary [1].

Biological context of octanoic acid


Anatomical context of octanoic acid

  • The medium-chain fatty acid sodium caprylate released 6-carboxyfluorescein (CF), a model compound of water-soluble drugs, from the rat small intestinal brush border membrane (BBM) vesicles and liposomes containing CF [8].

Associations of octanoic acid with other chemical compounds


  1. Inactivation of escherichia coli O157:H7 in cattle drinking water by sodium caprylate. Amalaradjou, M.A., Annamalai, T., Marek, P., Rezamand, P., Schreiber, D., Hoagland, T., Venkitanarayanan, K. J. Food Prot. (2006) [Pubmed]
  2. Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. Grekin, R.J., Vollmer, A.P., Sider, R.S. Hypertension (1995) [Pubmed]
  3. Serologic activity of fatty acid dependent antibodies in albumin-free systems. Beck, M.L., Edwards, R.L., Pierce, S.R., Hicklin, B.L., Bayer, W.L. Transfusion (1976) [Pubmed]
  4. Another potential source of error in Rh-hr typing. Reid, M.E., Ellisor, S.S., Frank, B.A. Transfusion (1975) [Pubmed]
  5. Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers. Wang, J., Lu, W.L., Liang, G.W., Wu, K.C., Zhang, C.G., Zhang, X., Wang, J.C., Zhang, H., Wang, X.Q., Zhang, Q. Peptides (2006) [Pubmed]
  6. Role of paracellular pathway in nonelectrolyte permeation across rat colon epithelium enhanced by sodium caprate and sodium caprylate. Sawada, T., Ogawa, T., Tomita, M., Hayashi, M., Awazu, S. Pharm. Res. (1991) [Pubmed]
  7. Determination of sodium caprylate in plasma volume expanders by gas chromatography. Lee, Y.C., Johnson, J.H. J. Chromatogr. (1986) [Pubmed]
  8. Fluorescence study of the membrane-perturbing action of sodium caprylate as related to promotion of drug absorption. Kajii, H., Horie, T., Hayashi, M., Awazu, S. Journal of pharmaceutical sciences. (1988) [Pubmed]
  9. Effects of fluorinated and hydrogenated surfactants on human serum albumin at different pHs. Sabín, J., Prieto, G., González-Pérez, A., Ruso, J.M., Sarmiento, F. Biomacromolecules (2006) [Pubmed]
  10. Effect of absorption promoters in intranasal administration of human fibroblast interferon as a powder dosage form in rabbits. Igawa, T., Maitani, Y., Machida, Y., Nagai, T. Chem. Pharm. Bull. (1989) [Pubmed]
  11. Bilirubin displacing effect of stabilizers added to injectable preparations of human serum albumin. Brodersen, R., Hansen, P. Acta paediatrica Scandinavica. (1977) [Pubmed]
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