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Chemical Compound Review

AC-Try     2-acetamido-3-(1H-indol-3- yl)propanoic acid

Synonyms: Acetyl-L-trp, Ac-DL-Trp-OH, PubChem10964, SureCN57140, AG-E-47635, ...
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Disease relevance of N-Acetyl-D-tryptophan


Psychiatry related information on N-Acetyl-D-tryptophan

  • Slow wave sleep (SWS) was enhanced after SP was microinjected into bilateral vLPO, while SP receptor antagonist, N-acetyl-l-tryptophan 3,5-bis(trifluoromethyl)-benzyl ester, led to the opposite effect [2].

High impact information on N-Acetyl-D-tryptophan


Biological context of N-Acetyl-D-tryptophan


Associations of N-Acetyl-D-tryptophan with other chemical compounds


Gene context of N-Acetyl-D-tryptophan


  1. Albumin administration combined with phototherapy in treatment of hyperbilirubinaemia in low-birth-weight infants. Ebbesen, F., Brodersen, R. Acta paediatrica Scandinavica. (1981) [Pubmed]
  2. Substance P promotes sleep in the ventrolateral preoptic area of rats. Zhang, G., Wang, L., Liu, H., Zhang, J. Brain Res. (2004) [Pubmed]
  3. Location of the medium chain fatty acid site on human serum albumin. Residues involved and relationship to the indole site. Lee, I.Y., McMenamy, R.H. J. Biol. Chem. (1980) [Pubmed]
  4. A comparative study of the effect of L-tryptophan and its acetylated derivative N-acetyl-L-tryptophan on rat muricidal behavior. Broderick, P.A., Bridger, W.H. Biol. Psychiatry (1984) [Pubmed]
  5. Inhibition of human peptidyl dipeptidase (angiotensin I converting enzyme: kininase II) by human serum albumin and its fragments. Klauser, R.J., Robinson, C.J., Marinkovic, D.V., Erdös, E.G. Hypertension (1979) [Pubmed]
  6. Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange. Ghomashchi, F., Zhang, X., Liu, L., Gelb, M.H. Biochemistry (1995) [Pubmed]
  7. Synthesis and biological evaluation of NK1 antagonists derived from L-tryptophan. MacLeod, A.M., Cascieri, M.A., Merchant, K.J., Sadowski, S., Hardwicke, S., Lewis, R.T., MacIntyre, D.E., Metzger, J.M., Fong, T.M., Shepheard, S. J. Med. Chem. (1995) [Pubmed]
  8. Binding rates, O--S substitution effects, and the pH dependence of chymotrypsin reactions. Hirohara, H., Philipp, M., Bender, M.L. Biochemistry (1977) [Pubmed]
  9. Evaluation of equilibrium constants for the binding of N-acetyl-L-tryptophan to monomeric and dimeric forms of alpha-chymotrypsin. Tellam, R., de Jersey, J., Winzor, D.J. Biochemistry (1979) [Pubmed]
  10. Nutritive value of N-acetyl-L-tryptophan in man. Wegmann, H., Curtius, H.C., Gitzelmann, R., Otten, A. Helvetica paediatrica acta. (1979) [Pubmed]
  11. Synthesis and in vitro activities of NK-1 antagonists derived from L-tryptophan. Caliendo, G., Fiorino, F., Grieco, P., Perissutti, E., Santagada, V., Calignano, A., Mancuso, F., Albrizio, S. Farmaco (1997) [Pubmed]
  12. Quantitation of methionyl peptides in nanomole quantities by a fluorometric method. Anderson, W.L., Shechter, Y., Parikh, I. Anal. Biochem. (1978) [Pubmed]
  13. What causes the variation of polarization degree across the emission spectrum of proteins? Turoverov, K.K., Kuznetsova, I.M. Biophys. Chem. (1986) [Pubmed]
  14. Structural features of luliberin (luteinising hormone-releasing factor) inferred from fluorescence measurements. Shinitzky, M., Fridkin, M. Biochim. Biophys. Acta (1976) [Pubmed]
  15. Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons. Howe, H.E., Somponpun, S.J., Sladek, C.D. J. Neurosci. (2004) [Pubmed]
  16. Identification of L-tryptophan derivatives with potent and selective antagonist activity at the NK1 receptor. MacLeod, A.M., Merchant, K.J., Brookfield, F., Kelleher, F., Stevenson, G., Owens, A.P., Swain, C.J., Casiceri, M.A., Sadowski, S., Ber, E. J. Med. Chem. (1994) [Pubmed]
  17. In vitro and in vivo properties of recombinant human serum albumin from Pichia pastoris purified by a method of short processing time. Watanabe, H., Yamasaki, K., Kragh-Hansen, U., Tanase, S., Harada, K., Suenaga, A., Otagiri, M. Pharm. Res. (2001) [Pubmed]
  18. Selective ion monitoring of tryptophan, N-acetyltryptophan and kynurenine in human serum. Application to the in vivo measurement of tryptophan pyrrolase activity. Wegmann, H., Curtius, H.C., Redweik, U. J. Chromatogr. (1978) [Pubmed]
  19. In vivo deacetylation of N-acetyl amino acids by kidney acylases in mice and rats. A possible role of acylase system in mammalian kidneys. Endo, Y. Biochim. Biophys. Acta (1980) [Pubmed]
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