Disease relevance of methylarsonic acid

• Distribution and toxicity of monosodium methanearsonate following oral administration of the herbicide to dairy sheep and goats [1].

High impact information on methylarsonic acid

• The stereoselective synthesis of methyl monate C 2 is described using as a key step an ene-intramolecular modified Sakurai cyclization (IMSC) reaction to prepare tetrahydropyran 5 [2].
• Translocation and metabolic fate of monosodium methanearsonic acid in wheat (Triticum aestivum L) [3].
• Glutathione Synthetase activity was higher in cotton than in either of the cocklebur biotypes; MSMA did not affect its activity in cotton or either cocklebur biotype [4].
• Effects of long-term exposure of the red swamp crawfish Procambarus clarkii to a mixture of two herbicides, 2,4-dichlorophenoxyacetic acid and monosodium methanearsonate, and associated human health risks [5].
• A 20-y-old white male cocaine addict attempted suicide by drinking approximately 500 ml of a 16% monosodium methanearsenate solution [6].

Biological context of methylarsonic acid

• In vitro percutaneous absorption of monosodium methanearsonate and disodium methanearsonate in female B6C3F1 mice [7].
• Some effects of multiple, sublethal doses of monosodium methanearsonate (MSMA) herbicide on hematology, growth, and reproduction of laboratory mice [8].

Analytical, diagnostic and therapeutic context of methylarsonic acid

• Uptake, distribution and elimination of monosodium methanearsonate following long term oral administration of the herbicide to sheep and goats [9].
• Leaf cuticle waxes were extracted from monosodium methanearsonate (MSMA)-resistant (R) and -susceptible (S) common cocklebur (Xanthium strumarium L.) and cotton (Gossypium hirsutum L.) plants at 0, 3, 5, and 7 days after treatment (DAT) following 1x and 2x MSMA applications [10].

References