The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Methylarsonate     methylarsonic acid

Synonyms: HSDB 845, CCRIS 9324, AG-D-52390, MeAsO(OH)2, CHEMBL1743208, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of methylarsonic acid


High impact information on methylarsonic acid


Chemical compound and disease context of methylarsonic acid


Biological context of methylarsonic acid


Anatomical context of methylarsonic acid


Associations of methylarsonic acid with other chemical compounds


Gene context of methylarsonic acid


Analytical, diagnostic and therapeutic context of methylarsonic acid


  1. Subchronic toxicity study with ethylene-bis-(oxyethylene)-bis-(3-tert-butyl-4-hydroxy-5-methylhydro cin namate) in the cynomolgus monkey: lack of stimulation of the pituitary-thyroid-liver axis. Waechter, F., Beilstein, P., Burger, A.G., O'Connell, M., Fabreguettes, C., Forster, R., Weideli, H. Toxicol. Sci. (1999) [Pubmed]
  2. Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis. Wu, M.M., Chiou, H.Y., Hsueh, Y.M., Hong, C.T., Su, C.L., Chang, S.F., Huang, W.L., Wang, H.T., Wang, Y.H., Hsieh, Y.C., Chen, C.J. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  3. Abnormal methylation capacity in human liver cirrhosis. Geubel, A.P., Mairlot, M.C., Buchet, J.P., Dive, C., Lauwerys, R. International journal of clinical pharmacology research. (1988) [Pubmed]
  4. Enzymic reactions of phosphate analogs. Gardner, J.H., Byers, L.D. J. Biol. Chem. (1977) [Pubmed]
  5. Spontaneous generation of stable pnictinyl radicals from "jack-in-the-box" dipnictines: a solid-state, gas-phase, and theoretical investigation of the origins of steric stabilization. Hinchley, S.L., Morrison, C.A., Rankin, D.W., Macdonald, C.L., Wiacek, R.J., Voigt, A., Cowley, A.H., Lappert, M.F., Gundersen, G., Clyburne, J.A., Power, P.P. J. Am. Chem. Soc. (2001) [Pubmed]
  6. Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh. Gamble, M.V., Liu, X., Ahsan, H., Pilsner, J.R., Ilievski, V., Slavkovich, V., Parvez, F., Chen, Y., Levy, D., Factor-Litvak, P., Graziano, J.H. Am. J. Clin. Nutr. (2006) [Pubmed]
  7. Atomization of hydride with a low-temperature, atmospheric pressure dielectric barrier discharge and its application to arsenic speciation with atomic absorption spectrometry. Zhu, Z., Zhang, S., Lv, Y., Zhang, X. Anal. Chem. (2006) [Pubmed]
  8. Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism. Nishikawa, T., Wanibuchi, H., Ogawa, M., Kinoshita, A., Morimura, K., Hiroi, T., Funae, Y., Kishida, H., Nakae, D., Fukushima, S. Int. J. Cancer (2002) [Pubmed]
  9. The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds. Hirano, S., Kobayashi, Y., Cui, X., Kanno, S., Hayakawa, T., Shraim, A. Toxicol. Appl. Pharmacol. (2004) [Pubmed]
  10. Arsenite uptake and metabolism by rat hepatocyte primary cultures in comparison with kidney- and hepatocyte-derived rat cell lines. Tatum, F.M., Hood, R.D. Toxicol. Sci. (1999) [Pubmed]
  11. A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species. Aposhian, H.V., Zakharyan, R.A., Avram, M.D., Sampayo-Reyes, A., Wollenberg, M.L. Toxicol. Appl. Pharmacol. (2004) [Pubmed]
  12. Study on the toxic effects induced by different arsenicals in primary cultured rat astroglia. Jin, Y., Sun, G., Li, X., Li, G., Lu, C., Qu, L. Toxicol. Appl. Pharmacol. (2004) [Pubmed]
  13. Cytotoxic and genotoxic effects of As, MMA, and DMA on leukocytes and stimulated human lymphocytes. Sordo, M., Herrera, L.A., Ostrosky-Wegman, P., Rojas, E. Teratog., Carcinog. Mutagen. (2001) [Pubmed]
  14. The acute inhalation toxicology of the technical grade organoarsenical herbicides, cacodylic acid and disodium methanearsonic acid; a route comparison. Stevens, J.T., DiPasquale, L.C., Farmer, J.D. Bulletin of environmental contamination and toxicology. (1979) [Pubmed]
  15. An integrated pharmacokinetic and pharmacodynamic study of arsenite action. 1. Heme oxygenase induction in rats. Kitchin, K.T., Del Razo, L.M., Brown, J.L., Anderson, W.L., Kenyon, E.M. Teratog., Carcinog. Mutagen. (1999) [Pubmed]
  16. Induction of genotoxic damage is not correlated with the ability to methylate arsenite in vitro in the leukocytes of four mammalian species. Peng, B., Sharma, R., Mass, M.J., Kligerman, A.D. Environ. Mol. Mutagen. (2002) [Pubmed]
  17. Effects of cysteine on the cytotoxicity of arsenic compounds. Zhou, X., Yoshida, K., Kuroda, K., Endo, Y., Endo, G. Arch. Environ. Contam. Toxicol. (2003) [Pubmed]
  18. Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver. Zakharyan, R., Wu, Y., Bogdan, G.M., Aposhian, H.V. Chem. Res. Toxicol. (1995) [Pubmed]
  19. Speciation determination of arsenic in urine by high-performance liquid chromatography-hydride generation atomic absorption spectrometry with on-line ultraviolet photooxidation. Tsalev, D.L., Sperling, M., Welz, B. The Analyst. (1998) [Pubmed]
  20. Bacterial degradation of arsenobetaine via dimethylarsinoylacetate. Jenkins, R.O., Ritchie, A.W., Edmonds, J.S., Goessler, W., Molenat, N., Kuehnelt, D., Harrington, C.F., Sutton, P.G. Arch. Microbiol. (2003) [Pubmed]
  21. Application of sample pre-oxidation of arsenite in human urine prior to speciation via on-line photo-oxidation with membrane hydride generation and ICP-MS detection. Wei, X., Brockhoff-Schwegel, C.A., Creed, J.T. The Analyst. (2000) [Pubmed]
  22. Functional characterization of two variant human GSTO 1-1s (Ala140Asp and Thr217Asn). Tanaka-Kagawa, T., Jinno, H., Hasegawa, T., Makino, Y., Seko, Y., Hanioka, N., Ando, M. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  23. Presence and distribution of arsenical species in beers. Herce-Pagliai, C., González, G., Camean, A.M., Repetto, M. Food additives and contaminants. (1999) [Pubmed]
  24. Endonuclease III, formamidopyrimidine-DNA glycosylase, and proteinase K additively enhance arsenic-induced DNA strand breaks in human cells. Wang, T.S., Chung, C.H., Wang, A.S., Bau, D.T., Samikkannu, T., Jan, K.Y., Cheng, Y.M., Lee, T.C. Chem. Res. Toxicol. (2002) [Pubmed]
  25. Arsenate reductase II. Purine nucleoside phosphorylase in the presence of dihydrolipoic acid is a route for reduction of arsenate to arsenite in mammalian systems. Radabaugh, T.R., Sampayo-Reyes, A., Zakharyan, R.A., Aposhian, H.V. Chem. Res. Toxicol. (2002) [Pubmed]
  26. Arsenic methylation capability and hypertension risk in subjects living in arseniasis-hyperendemic areas in southwestern Taiwan. Huang, Y.K., Tseng, C.H., Huang, Y.L., Yang, M.H., Chen, C.J., Hsueh, Y.M. Toxicol. Appl. Pharmacol. (2007) [Pubmed]
  27. DMPS-arsenic challenge test. I: Increased urinary excretion of monomethylarsonic acid in humans given dimercaptopropane sulfonate. Aposhian, H.V., Arroyo, A., Cebrian, M.E., del Razo, L.M., Hurlbut, K.M., Dart, R.C., Gonzalez-Ramirez, D., Kreppel, H., Speisky, H., Smith, A., Gonsebatt, M.E., Ostrosky-Wegman, P., Aposhian, M.M. J. Pharmacol. Exp. Ther. (1997) [Pubmed]
  28. Arsenic speciation by micellar liquid chromatography with inductively coupled plasma mass spectrometric detection. Ding, H., Wang, J., Dorsey, J.G., Caruso, J.A. Journal of chromatography. A. (1995) [Pubmed]
  29. Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide. Fujisawa, S., Ohno, R., Shigeno, K., Sahara, N., Nakamura, S., Naito, K., Kobayashi, M., Shinjo, K., Takeshita, A., Suzuki, Y., Hashimoto, H., Kinoshita, K., Shimoya, M., Kaise, T., Ohnishi, K. Cancer Chemother. Pharmacol. (2007) [Pubmed]
  30. Inorganic pentavalent arsenic methylation by rats: effect of concentration and dichromate. Gonzalez, M.J., Aguilar, M.V., Martinez, M.C. Veterinary and human toxicology. (1995) [Pubmed]
WikiGenes - Universities