Disease relevance of NSC 60534

• The authors present a previously unreported foreign-body reaction to poly-p-dioxanone pin fixation of a distal first metatarsal head osteotomy [1].
• Between January 1997 and July 2000, 10 patients with symptomatic bunionette deformity underwent 12 distal fifth metatarsal chevron osteotomies in which an absorbable poly-p-dioxanone suture (PDS) pin was used for fixation [2].
• Our experience suggests that poly-p-dioxanone pins are at least as effective as K wires, and the previous reports of inflammatory sinus formation and osteolysis are not a significant concern in the fixation of chevron osteotomies for hallux valgus [3].

High impact information on NSC 60534

• [reaction: see text] Pauson-Khand cyclization of dioxanone photoadduct 21 leads to the formation of a single product in good yield [4].
• Ectopic bone formation in mice associated with a lactic acid/dioxanone/ethylene glycol copolymer-tricalcium phosphate composite with added recombinant human bone morphogenetic protein-2 [5].
• Poly-p-dioxanone (PDS II) suture lost strength to a significant extent at pH 1.0, suggesting that care should be taken when this suture is used for closing tissues in contact with acidic media, such as the stomach [6].
• We evaluated one surgeon's (J.K.D.) results of distal chevron osteotomy fixation with a single, nonpredrilled, 1.3-mm poly-p-dioxanone pin and analyzed any differences in patients with unilateral or bilateral symptomatic metatarsus primus varus with hallux valgus deformities [7].

Anatomical context of NSC 60534

• A retrospective review of the medical records and radiographs of 32 consecutive patients, totaling 52 extremities with chevron osteotomies for hallux valgus, was conducted to compare K wire fixation with absorbable (poly-p-dioxanone) pin fixation [3].

Analytical, diagnostic and therapeutic context of NSC 60534

• We studied the outcome and complications seen with use of poly-p-dioxanone pins and those seen with use of stainless-steel Kirschner wires after chevron bunionectomy in 114 patients (144 feet) [8].
• OBJECTIVE: An absorbable pin made from poly-p-dioxanone (Orthosorb, Johnson and Johnson, UK) was used to internally fix osteotomies of the mandibular ramus [9].

References