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Chemical Compound Review

AC1L4NQC     3-(4-hydroxy-3,5-ditert- butyl...

Synonyms: DNC001300, AR-1L2057, SC-41661A, AC1Q3E0L, SC41661A, ...
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Disease relevance of 3-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanyl-N-methyl-N-(2-pyridin-2-ylethyl)propanamide

 

High impact information on 3-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanyl-N-methyl-N-(2-pyridin-2-ylethyl)propanamide

 

Biological context of 3-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanyl-N-methyl-N-(2-pyridin-2-ylethyl)propanamide

References

  1. Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase. Anderson, K.M., Levin, J., Jajeh, A., Seed, T., Harris, J.E. Prostaglandins Leukot. Essent. Fatty Acids (1993) [Pubmed]
  2. The mode of cell death in H-358 lung cancer cells cultured with inhibitors of 5-lipoxygenase or the free radical spin trap, NTBN. Ou, D., Bonomi, P., Jao, W., Jadko, S., Harris, J.E., Anderson, K.M. Cancer Lett. (2001) [Pubmed]
  3. Morphologic changes of apoptosis induced in human chronic myelogenous leukemia "blast" cells by SC41661A (Searle), a selective inhibitor of 5-lipoxygenase. Anderson, K.M., Seed, T.M., Peng, J., Jajeh, A., Meng, J., Harris, J.E. Scanning Microsc. (1994) [Pubmed]
  4. 5-Lipoxygenase inhibitors reduce PC-3 cell proliferation and initiate nonnecrotic cell death. Anderson, K.M., Seed, T., Vos, M., Mulshine, J., Meng, J., Alrefai, W., Ou, D., Harris, J.E. Prostate (1998) [Pubmed]
  5. Contrasting effects of two arachidonate 5-lipoxygenase inhibitors on formyl-methionyl-leucyl-phenylalanine (fMLP) and complement fragment 5a induced human neutrophil superoxide generation. Kocan, G.P., Partis, R.A., Mueller, R.A., Smith, W.G., Nakao, A. Biochem. Pharmacol. (1994) [Pubmed]
  6. Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid. Anderson, K.M., Seed, T., Meng, J., Ou, D., Alrefai, W.A., Harris, J.E. Anticancer Res. (1998) [Pubmed]
  7. Selective inhibitors of 5-lipoxygenase reduce CML blast cell proliferation and induce limited differentiation and apoptosis. Anderson, K.M., Seed, T., Plate, J.M., Jajeh, A., Meng, J., Harris, J.E. Leuk. Res. (1995) [Pubmed]
 
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