Disease relevance of tribenoside

• Effects of tribenoside (Glyvenol) on experimental osteoarthrosis [1].
• Drug eruption due to tribenoside [2].
• We report a case of tribenoside-induced hypersensitivity syndrome associated with cytomegalovirus reactivation and investigation of the immunological characteristics of the circulating and skin-infiltrating lymphocytes [3].
• The in vitro effects of azathioprine, clofibrate and tribenoside on the cell-mediated immune response was studied in some vascular diseases [4].

High impact information on tribenoside

• Comparisons of articular cartilage from untreated and treated animals showed no qualitative differences in the alterations of the morphology and histopathology of the tribenoside treated specimens [5].
• The mode of action of tribenoside on connective tissue is discussed in relation and contrast to the inhibitory effect of most anti-inflammatory antirheumatics on anabolic cartilage metabolism [1].
• The results clearly demonstrate that the higher dose (150 mg/kg) of tribenoside had a significant inhibitory influence on the degenerative processes in the knee joints [1].
• The number of cell divisions in the regenerating tissue is not significantly altered by tribenoside in a concentration of 1:400,000 [6].
• Biotransformation of tribenoside into benzoic acid in man [7].

Anatomical context of tribenoside

• Stabilization of rat erythrocytes against the haemolytic effect of glass particles by tribenoside [8].

Analytical, diagnostic and therapeutic context of tribenoside

• We investigated the inhibitory effect of tribenoside on OA by histological techniques [5].
• The possible involvement of other mechanisms in the stimulated regeneration observed after treatment with tribenoside is discussed [6].
• In male mice aged 17-20 months, the oral administration of tribenoside in doses of 500 and 1,200 mg/kg weekly led to a significant (p less than 0.05) reduction in the overall arthrotic involvement [9].
• Tribenoside was given in daily oral doses of 50 and 150 mg/kg by cannulation into the crop [1].

References