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Chemical Compound Review:

Tramazolina N-(5,6,7,8- tetrahydronaphthalen-1-yl)- 4,5...

Synonyms: Tramazoline, Towk, Tramazolinum, Muconasal (TN), CHEMBL32573, ...

Sichletidis, L. et al., Robinson, R.L. et al., Walland, A., Steppeler, A. et al., González-Peñas, E. et al., et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Tramazoline

No responses could be elicited in the mesentery by tramazoline [1].
A rise in blood pressure induced by the intravenous injection of noradrenaline or tramazoline enhanced the rates of release of the catecholamines in the anterior hypothalamic area [2].
A comparison of pre- and postsynaptic alpha-adrenergic effects of phenylephrine and tramazoline on blood vessels of the rabbit in vivo [3].
The inhibitory effect of tramazoline on the reflex increase in blood pressure and heart rate was antagonized by the presynaptic alpha-adrenolytic drug yohimbine [4].
Of the remaining children, 290 were further examined: methacholine test was positive in 109, exercise test was positive in 67, nasal provocation test with histamine was positive in 244, and rhinodilation test with tramazoline was positive in 206 [5].

Anatomical context of Tramazoline

The presence of tramazoline (TMZ, CAS 74195-73-6) in the eye drops increases the levels of DCF in aqueous humor [6].

References

Functional characterization of the pre- and postjunctional alpha-adrenoceptors in the in situ perfused rat mesenteric vascular bed. Eikenburg, D.C. Eur. J. Pharmacol. (1984) [Pubmed]
Effects of short-lasting and long-lasting blood pressure changes on the release of endogenous catecholamines in the hypothalamus of the conscious, freely moving rabbit. Robinson, R.L., Dietl, H., Bald, M., Kraus, A., Philippu, A. Naunyn Schmiedebergs Arch. Pharmacol. (1983) [Pubmed]
A comparison of pre- and postsynaptic alpha-adrenergic effects of phenylephrine and tramazoline on blood vessels of the rabbit in vivo. Steppeler, A., Tanaka, T., Starke, K. Naunyn Schmiedebergs Arch. Pharmacol. (1978) [Pubmed]
Inhibition of somato-sympathetic reflex via peripheral presynaptic alha-adrenoceptors. Walland, A. Eur. J. Pharmacol. (1978) [Pubmed]
The prevalence of allergic asthma and rhinitis in children of Polichni, Thessaloniki. Sichletidis, L., Chloros, D., Tsiotsios, I., Gioulekas, D., Kyriazis, G., Spyratos, D., Charalambidou, O., Goutsikas, S. Allergologia et immunopathologia. (2004) [Pubmed]
Absorption of sodium diclofenac after ocular administration in rabbit. González-Peñas, E., Aldana, I., Esteras, A., Bruseghini, L., Gazzaniga, A., Gianesello, W. Arzneimittel-Forschung. (1998) [Pubmed]

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