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Chemical Compound Review

AGN-PC-00AP7I     4-(3,7-dihydroxy-10,13- dimethyl-2,3,4,5,6...

Synonyms: KST-1A1000, Oprea1_287603, AC1L1KTB, AC1Q1QZZ, AC1Q5VTP, ...
 
 
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Disease relevance of Chenodiol

 

High impact information on Chenodiol

 

Anatomical context of Chenodiol

 

Gene context of Chenodiol

References

  1. Effect of Clostridium butyricum on the formation and dissolution of gallstones in experimental cholesterol cholelithiasis. Takeda, Y., Itoh, H., Kobashi, K. Life Sci. (1983) [Pubmed]
  2. Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells. Li, T., Jahan, A., Chiang, J.Y. Hepatology (2006) [Pubmed]
  3. Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor. Ellis, E., Axelson, M., Abrahamsson, A., Eggertsen, G., Thörne, A., Nowak, G., Ericzon, B.G., Björkhem, I., Einarsson, C. Hepatology (2003) [Pubmed]
  4. Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA. Nakahara, M., Fujii, H., Maloney, P.R., Shimizu, M., Sato, R. J. Biol. Chem. (2002) [Pubmed]
  5. Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription. Chiang, J.Y., Kimmel, R., Weinberger, C., Stroup, D. J. Biol. Chem. (2000) [Pubmed]
  6. Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore. Rolo, A.P., Oliveira, P.J., Moreno, A.J., Palmeira, C.M. Biochem. Pharmacol. (2001) [Pubmed]
 
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