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Chemical Compound Review

Jumbo     sulfamic acid

Synonyms: Sulfamidsaeure, Sulphamic acid, SULFAMIC ACID, ARONIS25155, AGN-PC-0D24P5, ...
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Disease relevance of sulfamic acid


High impact information on sulfamic acid


Biological context of sulfamic acid


Anatomical context of sulfamic acid

  • At 50 and 100 micrograms/ml sulfamic acid diester, the half-time in whole blood is 6.9 h and 65% of the drug is sequestered by the blood cells [8].
  • Using an improved method for determination of total N-nitroso compounds (NOC), we examined the stability of those compounds in fresh gastric juice samples during storage and the effects of the addition of 2% sulphamic acid on NOC concentration in 212 samples [11].

Associations of sulfamic acid with other chemical compounds


Analytical, diagnostic and therapeutic context of sulfamic acid


  1. Aminosulfonic acid buffer preserves myocardium during prolonged ischemia. Swan, H., Cowan, M., Tornabene, M., Owens, L. Ann. Thorac. Surg. (1994) [Pubmed]
  2. Inhibitory effects of sulfamic acid on three thiosulfate-oxidizing chemolithotrophs. Lusty, J.R., Hughes, M.N., Kelly, D.P. FEMS Microbiol. Lett. (2006) [Pubmed]
  3. Sulfamates and their therapeutic potential. Winum, J.Y., Scozzafava, A., Montero, J.L., Supuran, C.T. Medicinal research reviews. (2005) [Pubmed]
  4. Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design. Abbate, F., Supuran, C.T., Scozzafava, A., Orioli, P., Stubbs, M.T., Klebe, G. J. Med. Chem. (2002) [Pubmed]
  5. Synthesis and physicochemical properties of sulfamate derivatives as topical antiglaucoma agents. Lo, Y.S., Nolan, J.C., Maren, T.H., Welstead, W.J., Gripshover, D.F., Shamblee, D.A. J. Med. Chem. (1992) [Pubmed]
  6. In vitro cytotoxicity of hepsulfam against human tumor cell lines and primary human tumor colony forming units. Marshall, M.V., Marshall, M.H., Degen, D.R., Roodman, G.D., Kuhn, J.G., Ross, M.E., Von Hoff, D.D. Stem Cells (1993) [Pubmed]
  7. Pharmacokinetics and metabolism of the antitumor agent sulfamic acid 1,7-heptanediyl ester (sulfamic acid diester) in the mouse and beagle dog. Brodfuehrer, J.I., Wilke, T.J., Powis, G. Cancer Chemother. Pharmacol. (1988) [Pubmed]
  8. Gas chromatographic assay for the new antitumor agent sulfamic acid diester (NSC 329680) and its stability in buffer, blood and plasma. Brodfuehrer, J.I., Powis, G. J. Chromatogr. (1988) [Pubmed]
  9. Partial purification from hot dogs of N-nitroso compound precursors and their mutagenicity after nitrosation. Zhou, L., Haorah, J., Perini, F., Carmella, S.G., Shibamoto, T., Mirvish, S.S. J. Agric. Food Chem. (2006) [Pubmed]
  10. Biological monitoring of workers exposed to 4,4'-methylene-bis-(2-orthochloroaniline) (MOCA). II. Comparative interest of "free" and "total" MOCA in the urine of exposed workers. Robert, A., Ducos, P., Francin, J.M. International archives of occupational and environmental health. (1999) [Pubmed]
  11. Instability of N-nitroso compounds in gastric juice and preliminary results from analyses of fresh samples by using an improved analytical method. Xu, G.P., Reed, P.I. Eur. J. Cancer Prev. (1993) [Pubmed]
  12. Mechanistic investigation of the degradation of sulfamic acid 1,7-heptanediyl ester, an experimental cytotoxic agent, in water and 18oxygen-enriched water. Paborji, M., Waugh, W.N., Stella, V.J. Journal of pharmaceutical sciences. (1987) [Pubmed]
  13. Development of physicochemical nitrogen removal process for high strength industrial wastewater. Lee, S., Maken, S., Jang, J.H., Park, K., Park, J.W. Water Res. (2006) [Pubmed]
  14. Determination of total N-nitroso compounds and their precursors in frankfurters, fresh meat, dried salted fish, sauces, tobacco, and tobacco smoke particulates. Haorah, J., Zhou, L., Wang, X., Xu, G., Mirvish, S.S. J. Agric. Food Chem. (2001) [Pubmed]
  15. 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors. Klopfenstein, S.R., Evdokimov, A.G., Colson, A.O., Fairweather, N.T., Neuman, J.J., Maier, M.B., Gray, J.L., Gerwe, G.S., Stake, G.E., Howard, B.W., Farmer, J.A., Pokross, M.E., Downs, T.R., Kasibhatla, B., Peters, K.G. Bioorg. Med. Chem. Lett. (2006) [Pubmed]
  16. Sulfamic acid cleaning solution for 4,4'-methylene-bisorthochloroaniline (MOCA). Schmitt, C.R., Cagle, G.W. American Industrial Hygiene Association journal. (1975) [Pubmed]
  17. Sulfamic acid as a standard substance in non-aqueous titrimetry. Przyborowski, L. Annales Universitatis Mariae Curie-Skłodowska. Sectio D: Medicina. (1975) [Pubmed]
  18. Induction and suppression of aminosulfonic acid spikes in Wulst EEG of adult chickens. Horisaka, K. J. Pharmacobio-dyn. (1982) [Pubmed]
  19. Investigation of the drying conditions for amidosulfuric acid. Asakai, T., Minegishi, R., Inaba, N., Ishimura, Y., Murayama, M., Tanaka, T. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. (2006) [Pubmed]
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