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Chemical Compound Review

sJPhLQbIKTp@     2-bromoethanoic acid

Synonyms: PubChem13144, NSC-141, CHEMBL60851, NSC141, CCRIS 7886, ...
 
 
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Disease relevance of Acide bromacetique

 

High impact information on Acide bromacetique

 

Biological context of Acide bromacetique

 

Anatomical context of Acide bromacetique

  • BA was more cytotoxic (31x) and genotoxic (14x) than MX in CHO cells [8].
 

Associations of Acide bromacetique with other chemical compounds

  • N-carboxymethyl amino acids were synthesized by alkylation using bromoacetic acid ester and the N-carboxyethyl amino acids via reductive alkylation using aldehydes derived from formyl Meldrums acid [9].
  • A potential affinity analog, the bromoacetamide derivative of the amino compound, has been synthesized in both unlabeled and 14C-labeled forms via a condensation of bromoacetic acid with the amino compound using DCC [10].

References

  1. Acute spermatogenic effects of bromoacetic acids. Linder, R.E., Klinefelter, G.R., Strader, L.F., Suarez, J.D., Dyer, C.J. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1994) [Pubmed]
  2. Incorporation of unprotected heterocyclic side chains into peptoid oligomers via solid-phase submonomer synthesis. Burkoth, T.S., Fafarman, A.T., Charych, D.H., Connolly, M.D., Zuckermann, R.N. J. Am. Chem. Soc. (2003) [Pubmed]
  3. Similarities in structure between holocytochrome b5 and apocytochrome b5: NMR studies of the histidine residues. Moore, C.D., al-Misky, O.N., Lecomte, J.T. Biochemistry (1991) [Pubmed]
  4. The kinetics and specificity of the reaction of 2'(3')-O-bromoacetyluridine with bovine pancreatic ribonuclease A. Pincus, M., Thi, L.L., Carty, R.P. Biochemistry (1975) [Pubmed]
  5. Synthesis, structure, and X-band (9.5 GHz) EPR characterization of the new series of pH-sensitive spin probes: N,N-disubstituted 4-amino-2,2,5,5-tetramethyl-3-imidazoline 1-oxyls. Voinov, M.A., Polienko, J.F., Schanding, T., Bobko, A.A., Khramtsov, V.V., Gatilov, Y.V., Rybalova, T.V., Smirnov, A.I., Grigor'ev, I.A. J. Org. Chem. (2005) [Pubmed]
  6. Kinetics of inhibition of beta-glucosidase from Ampullarium crossean by bromoacetic acid. Chen, Q.X., Zhang, Z., Zhou, X.W., Zhuang, Z.L. Int. J. Biochem. Cell Biol. (2000) [Pubmed]
  7. Synthesis of 2-(p-thiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid: application of the 4-methoxy-2,3,6-trimethylbenzenesulfonamide protecting group in the synthesis of macrocyclic polyamines. McMurry, T.J., Brechbiel, M., Wu, C., Gansow, O.A. Bioconjug. Chem. (1993) [Pubmed]
  8. Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products. Plewa, M.J., Kargalioglu, Y., Vankerk, D., Minear, R.A., Wagner, E.D. Environ. Mol. Mutagen. (2002) [Pubmed]
  9. Synthesis of N-carboxyalkyl and N-aminoalkyl functionalized dipeptide building units for the assembly of backbone cyclic peptides. Müller, B., Besser, D., Kleinwächter, P., Arad, O., Reissmann, S. J. Pept. Res. (1999) [Pubmed]
  10. Covalent modification of aromatase by a radiolabeled irreversible inhibitor. Snider, C.E., Brueggemeier, R.W. J. Steroid Biochem. (1985) [Pubmed]
 
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