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Chemical Compound Review

PubChem3257     2-bromo-1-phenyl-ethanone

Synonyms: Stauffer 4644, AGN-PC-00D5CR, CHEMBL102953, NSC-9807, ACMC-1BG71, ...
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High impact information on NSC 9807


Associations of NSC 9807 with other chemical compounds


Gene context of NSC 9807

  • Treatment of lecithin-cholesterol acyltransferase or B10-reacting phospholipases with phenacyl bromide, a reagent known to interact with the active site of phospholipase A2, inhibited both their esterolytic activity and their capacity to bind to B10 [9].
  • Two photoactivable reagents were used: para azido phenacyl bromide (pAPA) which reacts with the SH of the ACP prosthetic group and the N-hydroxysuccinimide ester of 4-azido salicylic acid (NHS-ASA) which reacts with the amino groups of the protein [10].
  • ((1977) Biochem. Biophys. Res. Commun. 74, 384-389) that phenacyl bromide reacts with a single reactive sulfhydryl group of aconitase, abolishing enzyme activity [11].

Analytical, diagnostic and therapeutic context of NSC 9807

  • Twenty-two biologically relevant (6:0-22:6) saturated, monounsaturated and polyunsaturated fatty acids were separated by reversed-phase high-performance liquid chromatography after derivatization with phenacyl bromide [12].


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  2. Bromoacetophenone as an affinity reagent for human liver aldehyde dehydrogenase. MacKerell, A.D., MacWright, R.S., Pietruszko, R. Biochemistry (1986) [Pubmed]
  3. Synthesis of 1-aryl-1H-indazoles via palladium-catalyzed intramolecular amination of aryl halides. Lebedev, A.Y., Khartulyari, A.S., Voskoboynikov, A.Z. J. Org. Chem. (2005) [Pubmed]
  4. Photolabeling of mitochondrial F1-ATPase by an azido derivative of the oligomycin-sensitivity conferring protein. Dupuis, A., Vignais, P.V. Biochem. Biophys. Res. Commun. (1985) [Pubmed]
  5. Application of quantitative structure-activity relationship modeling to the evaluation of the changes in enzymatic activity of carboxypeptidase Y upon chemical modifications. Kanstrup, A., Breddam, K., Buchardt, O. Arch. Biochem. Biophys. (1993) [Pubmed]
  6. High-performance liquid chromatographic determination of cytosine-containing compounds by precolumn fluorescence derivatization with phenacyl bromide: application to antiviral nucleosides and nucleotides. Eisenberg, E.J., Cundy, K.C. J. Chromatogr. B, Biomed. Appl. (1996) [Pubmed]
  7. Major metabolites of zolpidem: expeditious synthesis and mass spectra. Klupsch, F., Houssin, R., Humbert, L., Imbenotte, M., Hénichart, J.P., Lhermitte, M. Chem. Pharm. Bull. (2006) [Pubmed]
  8. Fluorimetric analysis of phospholipase activity in Tetrahymena pyriformis GL. Kovács, P., Csaba, G. Biosci. Rep. (1999) [Pubmed]
  9. Antigenic relatedness between human lecithin-cholesterol acyltransferase and phospholipases of the A2 family. Khalil, A., Farooqui, J., Scanu, A.M. Biochim. Biophys. Acta (1986) [Pubmed]
  10. Photoaffinity cross-linking of acyl carrier protein to Escherichia coli membranes. Bayan, N., Thérisod, H. Biochim. Biophys. Acta (1992) [Pubmed]
  11. A spin-label study of the disposition of the Fe-S cluster with respect to the active center of aconitase. Dreyer, J.L., Beinert, H., Keana, J.F., Hankovszky, O.H., Hideg, K., Eaton, S.S., Eaton, G.R. Biochim. Biophys. Acta (1983) [Pubmed]
  12. Determination of fatty acids as phenacyl esters in rat adipose tissue and blood vessel walls by high-performance liquid chromatography. Hanis, T., Smrz, M., Klir, P., Macek, K., Klima, J., Base, J., Deyl, Z. J. Chromatogr. (1988) [Pubmed]
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