High impact information on 13-Hydroperoxylinoleic acid

• Uptake of 13-hydroperoxylinoleic acid by cultured cells [1].
• Analysis of the reaction between 2'-deoxyadenosine and 13-hydroperoxylinoleic acid by liquid chromatography/constant neutral loss mass spectrometry revealed the presence of two major products (adducts A and B) [2].
• The role of endothelial cells in the relaxations induced by 13-hydroxy- and 13-hydroperoxylinoleic acid in canine arteries [3].
• In mixed micelles, H2O2 shortened the induction period, while 13-hydroperoxylinoleic acid and t-butyl hydroperoxide completely removed it [4].
• Self-inactivation by 13-hydroperoxylinoleic acid and lipohydroperoxidase activity of the reticulocyte lipoxygenase [5].

Biological context of 13-Hydroperoxylinoleic acid

• In this study we investigate the effect of several bile acids (cholate, deoxycholate, chenodeoxycholate) and 13-hydroperoxylinoleic acid (conc. 0.1-1000, microM) on human colonic lamina propria lymphocyte (LPL) DNA synthesis and cell proliferation [6].

Associations of 13-Hydroperoxylinoleic acid with other chemical compounds

• 5. To observe maximal dioxygenase activity (about 0.7 mumol of 13-hydroperoxylinoleic acid formed/min per mg protein) at pH 9.5, the presence of 6.0 mM linoleic acid was required [7].
• HPO lyases I and II from hypocotyl metabolized 13-hydroperoxylinoleic acid and 13-hydroperoxylinolenic acid to the same extent, but the green leaf enzyme was more than ten-fold more active with 13-hydroperoxylinolenic acid than 13-hydroperoxylinoleic acid [8].

Gene context of 13-Hydroperoxylinoleic acid

• 13-Hydroperoxylinoleic acid inhibits rat liver glyoxalase II [9].

References