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Gene Review

Hagh  -  hydroxyacyl glutathione hydrolase

Rattus norvegicus

Synonyms: Glo2, Glx II, Glyoxalase II, Hydroxyacylglutathione hydrolase, mitochondrial, RSP29, ...
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Analytical, diagnostic and therapeutic context of Hagh


  1. Characterization of proteolipid protein fatty acylesterase from rat brain myelin. Bizzozero, O.A., Leyba, J., Nuñez, D.J. J. Biol. Chem. (1992) [Pubmed]
  2. Glyoxalase II and glutathione levels in rat liver mitochondria during cold storage in Euro-Collins and University of Wisconsin solutions. Jassem, W., Ciarimboli, C., Cerioni, P.N., Saba, V., Norton, S.J., Principato, G. Transplantation (1996) [Pubmed]
  3. Diffusion-dependent rates for the hydrolysis reaction catalyzed by glyoxalase II from rat erythrocytes. Guha, M.K., Vander Jagt, D.L., Creighton, D.J. Biochemistry (1988) [Pubmed]
  4. S-(nitrocarbobenzoxy)glutathiones: potent competitive inhibitors of mammalian glyoxalase II. Bush, P.E., Norton, S.J. J. Med. Chem. (1985) [Pubmed]
  5. cDNA cloning and characterization of a rat spermatogenesis-associated protein RSP29. Ji, X., Moore, H.D., Russell, R.G., Watts, D.J. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  6. S-2-hydroxyacylglutathione hydrolase (glyoxalase II): active-site mapping of a nonserine thiolesterase. Ball, J.C., Vander Jagt, D.L. Biochemistry (1981) [Pubmed]
  7. Modification of the glyoxalase system in streptozotocin-induced diabetic rats. Effect of the aldose reductase inhibitor Statil. Phillips, S.A., Mirrlees, D., Thornalley, P.J. Biochem. Pharmacol. (1993) [Pubmed]
  8. Isolation of glyoxalase II from two different compartments of rat liver mitochondria. Kinetic and immunochemical characterization of the enzymes. Talesa, V., Uotila, L., Koivusalo, M., Principato, G., Giovannini, E., Rosi, G. Biochim. Biophys. Acta (1989) [Pubmed]
  9. 13-Hydroperoxylinoleic acid inhibits rat liver glyoxalase II. Gillespie, E. Inflammation (1981) [Pubmed]
  10. Evaluation of the fluidity and functionality of the renal cortical brush border membrane in experimental diabetes in rats. Limaye, P.V., Sivakami, S. Int. J. Biochem. Cell Biol. (2003) [Pubmed]
  11. Biochemical changes in transplanted rat liver stored in University of Wisconsin and Euro-Collins solutions. Jassem, W., Battino, M., Cinti, C., Norton, S.J., Saba, V., Principato, G. J. Surg. Res. (2000) [Pubmed]
  12. Multimeric forms of rat liver glyoxalase II. Hsu, Y.R., Norton, S.J. Enzyme (1983) [Pubmed]
  13. Purification and characterization of two forms of glyoxalase II from the liver and brain of Wistar rats. Principato, G.B., Rosi, G., Talesa, V., Giovannini, E., Uotila, L. Biochim. Biophys. Acta (1987) [Pubmed]
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