Disease relevance of isopropyl acetate

• The toxicity of isopropyl acetate (IPA), an organic solvent with a similar chemical structure, was examined similarly [1].

High impact information on isopropyl acetate

• CONCLUSIONS: Ethyl propionate and isopropyl acetate are less toxic to the intestinal mucosa than MTBE, and ethyl propionate is more effective for gallstone dissolution [2].
• The in vitro effectiveness of three new cholesterol gallstone solvents that have a potential for clinical use--ethyl propionate, isopropyl acetate, and n-propyl acetate--was compared with that of the well-known cholesterol solvent methyl tert-butyl ether (MTBE) [3].
• Racemic 1-(9-anthryl)ethylamine (10), obtained in 70% overall yield from commercial 9-cyanoanthracene, was kinetically resolved by the Candida antarctica A lipase-catalyzed acetylation with isopropyl acetate as acyl donor, affording (R)-(+)-10 with 95.8% enantiomeric excess (e.e.) (E-value 43.5), which afforded Schiff bases (R)-4 and(R)-8 [4].
• 3. Biomimetic oxidation studies with peroxytrifluoroacetic acid of a simple model of the herbicide (isopropyl acetate) have provided confirmation of the feasibility of the novel biotransformation [5].
• Ethanolic extract, isopropyl acetate fraction and gallic acid reduced significantly larval growth of S. frugiperda neonates [6].

Analytical, diagnostic and therapeutic context of isopropyl acetate

• The addition of a bridging liquid (isopropyl acetate) improved spherical crystallization [7].

References