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Chemical Compound Review

CCRIS 1806     (2S)-2-amino-4-[[(1S)-1...

Synonyms: CHEBI:8927, AC1L3YPO, CTK4F7569, AR-1J3587, LS-188540, ...
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High impact information on 32728-50-0


Biological context of 32728-50-0

  • Sarcolemmal vesicles prepared from rat heart exhibited ATP-dependent uptake of S-(2,4-dinitrophenyl)glutathione (DNP-SG), which obeyed Michaelis-Menten kinetics with an apparent Km of 21 microM for DNP-SG and a Vmax of 0.27 nmol.10 protein-1 [4].

Anatomical context of 32728-50-0


Associations of 32728-50-0 with other chemical compounds


Gene context of 32728-50-0


  1. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. Wijnholds, J., Mol, C.A., van Deemter, L., de Haas, M., Scheffer, G.L., Baas, F., Beijnen, J.H., Scheper, R.J., Hatse, S., De Clercq, E., Balzarini, J., Borst, P. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  2. Adenosine triphosphate-dependent transport of estradiol-17beta(beta-D-glucuronide) in membrane vesicles by MDR1 expressed in insect cells. Huang, L., Hoffman, T., Vore, M. Hepatology (1998) [Pubmed]
  3. Organic anion-transporting ATPase of rat liver. I. Purification, photoaffinity labeling, and regulation by phosphorylation. Pikula, S., Hayden, J.B., Awasthi, S., Awasthi, Y.C., Zimniak, P. J. Biol. Chem. (1994) [Pubmed]
  4. Leukotriene C4 inhibits ATP-dependent transport of glutathione S-conjugate across rat heart sarcolemma. Implication for leukotriene C4 translocation mediated by glutathione S-conjugate carrier. Ishikawa, T. FEBS Lett. (1989) [Pubmed]
  5. ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver. Akerboom, T.P., Narayanaswami, V., Kunst, M., Sies, H. J. Biol. Chem. (1991) [Pubmed]
  6. ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates. A study using rat heart sarcolemma vesicles. Ishikawa, T. J. Biol. Chem. (1989) [Pubmed]
  7. Organic anions exhibit distinct inhibition patterns on the low-Km and high-Km transport of S-(2,4-dinitrophenyl)glutathione through the human erythrocyte membrane. Bartosz, G., Sies, H., Akerboom, T.P. Biochem. J. (1993) [Pubmed]
  8. ATP-dependent transport of beta-estradiol 17-(beta-D-glucuronide) in rat canalicular membrane vesicles. Vore, M., Hoffman, T., Gosland, M. Am. J. Physiol. (1996) [Pubmed]
  9. Characterization of organic anion transporter regulation, glutathione metabolism and bile formation in the obese Zucker rat. Geier, A., Dietrich, C.G., Grote, T., Beuers, U., Prüfer, T., Fraunberger, P., Matern, S., Gartung, C., Gerbes, A.L., Bilzer, M. J. Hepatol. (2005) [Pubmed]
  10. Purification and characterization of dinitrophenylglutathione ATPase of human erythrocytes and its expression in other tissues. Sharma, R., Gupta, S., Singh, S.V., Medh, R.D., Ahmad, H., LaBelle, E.F., Awasthi, Y.C. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
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