High impact information on Gsg1

• Germ cell-specific transcripts are much less common earlier in testis development [1].
• Germ cell-specific enhancer activity of a repeated element in a variable region of the mouse genome [2].
• Germ-cell specific protein gametogenetin protein 2 (GGN2), expression in the testis, and association with intracellular membrane [3].
• Germ cell specific promoter drives ectopic transgene expression during embryogenesis [4].
• Germ cell-specific Tfam transcript isoforms are expressed during spermatogenesis in mice and humans [5].

Biological context of Gsg1

• Germ cell-specific apoptosis after IR of the testis has been shown to be correlated with and dependent on neutrophil recruitment to the testis after IR [6].
• Germ cell-specific expression of a proacrosin-CAT fusion gene in transgenic mouse testis [7].
• Germ cell-specific decrease of acrosomal proteolytic activity, sperm motility, and number in mitomycin C-treated mice [8].

Anatomical context of Gsg1

• Germ cell-specific DNA and RNA binding proteins p48/52 are expressed at specific stages of male germ cell development and are present in the chromatoid body [9].

Other interactions of Gsg1

• Germ cell-specific expression of microphthalmia-associated transcription factor mRNA in mouse testis [10].

References