Gene Review:
Mitf - microphthalmia-associated transcription...
Mus musculus
Synonyms:
BCC2, Bhlhe32, Bw, Gsfbcc2, Mi, ...
- Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. McGill, G.G., Horstmann, M., Widlund, H.R., Du, J., Motyckova, G., Nishimura, E.K., Lin, Y.L., Ramaswamy, S., Avery, W., Ding, H.F., Jordan, S.A., Jackson, I.J., Korsmeyer, S.J., Golub, T.R., Fisher, D.E. Cell (2002)
- Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development. Steingrimsson, E., Tessarollo, L., Pathak, B., Hou, L., Arnheiter, H., Copeland, N.G., Jenkins, N.A. Proc. Natl. Acad. Sci. U.S.A. (2002)
- White mutants in mice shedding light on humans. Halaban, R., Moellmann, G. J. Invest. Dermatol. (1993)
- Mutation in intron 6 of the hamster Mitf gene leads to skipping of the subsequent exon and creates a novel animal model for the human Waardenburg syndrome type II. Graw, J., Pretsch, W., Löster, J. Genetics (2003)
- Transient overexpression of the Microphthalmia gene in the eyes of Microphthalmia vitiligo mutant mice. Bora, N., Conway, S.J., Liang, H., Smith, S.B. Dev. Dyn. (1998)
- Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences. Steingrímsson, E., Moore, K.J., Lamoreux, M.L., Ferré-D'Amaré, A.R., Burley, S.K., Zimring, D.C., Skow, L.C., Hodgkinson, C.A., Arnheiter, H., Copeland, N.G. Nat. Genet. (1994)
- Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene. Tassabehji, M., Newton, V.E., Read, A.P. Nat. Genet. (1994)
- MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes. Hemesath, T.J., Price, E.R., Takemoto, C., Badalian, T., Fisher, D.E. Nature (1998)
- Levels of retinoic acid and retinaldehyde dehydrogenase expression in eyes of the Mitf-vit mouse model of retinal degeneration. Duncan, T., Swint, C., Smith, S.B., Wiggert, B.N. Mol. Vis. (1999)
- Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo. Trcka, J., Moroi, Y., Clynes, R.A., Goldberg, S.M., Bergtold, A., Perales, M.A., Ma, M., Ferrone, C.R., Carroll, M.C., Ravetch, J.V., Houghton, A.N. Immunity (2002)
- Anti-epileptogenic effect of beta-carotene and vitamin A in pentylenetetrazole-kindling model of epilepsy in mice. Sayyah, M., Yousefi-Pour, M., Narenjkar, J. Epilepsy Res. (2005)
- A new antithrombotic agent, aspalatone, attenuated cardiotoxicity induced by doxorubicin in the mouse; possible involvement of antioxidant mechanism. Kim, C., Nam, S.W., Choi, D.Y., Choi, J.H., Park, E.S., Jhoo, W.K., Kim, H.C. Life Sci. (1997)
- Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor. Lin, L., Gerth, A.J., Peng, S.L. J. Exp. Med. (2004)
- Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Rowan, S., Chen, C.M., Young, T.L., Fisher, D.E., Cepko, C.L. Development (2004)
- Otx genes are required for tissue specification in the developing eye. Martinez-Morales, J.R., Signore, M., Acampora, D., Simeone, A., Bovolenta, P. Development (2001)
- Signaling and transcriptional regulation in the neural crest-derived melanocyte lineage: interactions between KIT and MITF. Hou, L., Panthier, J.J., Arnheiter, H. Development (2000)
- The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor. Takemoto, C.M., Yoon, Y.J., Fisher, D.E. J. Biol. Chem. (2002)
- Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor. Opdecamp, K., Nakayama, A., Nguyen, M.T., Hodgkinson, C.A., Pavan, W.J., Arnheiter, H. Development (1997)
- Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation. Lee, J., Kim, K., Kim, J.H., Jin, H.M., Choi, H.K., Lee, S.H., Kook, H., Kim, K.K., Yokota, Y., Lee, S.Y., Choi, Y., Kim, N. Blood (2006)
- Mitf-PU.1 interactions with the tartrate-resistant acid phosphatase gene promoter during osteoclast differentiation. Partington, G.A., Fuller, K., Chambers, T.J., Pondel, M. Bone (2004)
- Systematic method to obtain novel genes that are regulated by mi transcription factor: impaired expression of granzyme B and tryptophan hydroxylase in mi/mi cultured mast cells. Ito, A., Morii, E., Maeyama, K., Jippo, T., Kim, D.K., Lee, Y.M., Ogihara, H., Hashimoto, K., Kitamura, Y., Nojima, H. Blood (1998)
- Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice. Tsujimura, T., Morii, E., Nozaki, M., Hashimoto, K., Moriyama, Y., Takebayashi, K., Kondo, T., Kanakura, Y., Kitamura, Y. Blood (1996)
- Involvement of transcription factor encoded by the mouse mi locus (MITF) in apoptosis of cultured mast cells induced by removal of interleukin-3. Tsujimura, T., Hashimoto, K., Morii, E., Tunio, G.M., Tsujino, K., Kondo, T., Kanakura, Y., Kitamura, Y. Am. J. Pathol. (1997)
- The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis. Vetrini, F., Auricchio, A., Du, J., Angeletti, B., Fisher, D.E., Ballabio, A., Marigo, V. Mol. Cell. Biol. (2004)
- Peripheral CD8+ T cell tolerance against melanocytic self-antigens in the skin is regulated in two steps by CD4+ T cells and local inflammation: implications for the pathophysiology of vitiligo. Steitz, J., Brück, J., Lenz, J., Büchs, S., Tüting, T. J. Invest. Dermatol. (2005)
- Pax3 down-regulation and shut-off of melanogenesis in melanoma B16/F10.9 by interleukin-6 receptor signaling. Kamaraju, A.K., Bertolotto, C., Chebath, J., Revel, M. J. Biol. Chem. (2002)
- Expression of tyrosinase and the tyrosinase related proteins in the Mitfvit (vitiligo) mouse eye: implications for the function of the microphthalmia transcription factor. Smith, S.B., Zhou, B.K., Orlow, S.J. Exp. Eye Res. (1998)
- Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Horsford, D.J., Nguyen, M.T., Sellar, G.C., Kothary, R., Arnheiter, H., McInnes, R.R. Development (2005)
- Interspecies difference in the regulation of melanocyte development by SOX10 and MITF. Hou, L., Arnheiter, H., Pavan, W.J. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Microphthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis. King, R., Weilbaecher, K.N., McGill, G., Cooley, E., Mihm, M., Fisher, D.E. Am. J. Pathol. (1999)
- Spontaneous transdifferentiation of quail pigmented epithelial cell is accompanied by a mutation in the Mitf gene. Mochii, M., Ono, T., Matsubara, Y., Eguchi, G. Dev. Biol. (1998)