Psychiatry related information on CTNNA2

• Standard sleep variables and CAP rates, referred to the ratio of CAP time to Total NREM sleep time (CAPR/NREM) and to each NREM sleep stage, were scored for statistical inferences and correlations [1].

High impact information on CTNNA2

• The CAP-R protein mostly differs from CAP102 by the presence of a 48-residue insert [2].
• Using in situ hybridization, the CAP-R gene could be mapped to the p11.1-p12 region of human chromosome 2 and to the homologous B3-D region of mouse chromosome 6 [2].
• A role of alpha-catenin in the recruitment of E-cadherin and ALCAM to cell-cell contacts was established by transfection of an alpha-N-catenin construct into cell lines ALVA-31 and PC-3 [3].
• The CAP-resistance phenotype of these hybrids changed abruptly when the proportion of CAP-R mtDNAs fluctuated around approximately 10% (threshold effect) [4].
• With increased genetic divergence, the acceptability of the CAP-R mitochondria decreased [5].

Anatomical context of CTNNA2

• A previous study issued from our laboratory demonstrated that alpha N-catenin is localized in the axoplasm of unmyelinated peripheral nerves, whereas the localization of alpha E-catenin in the peripheral nervous system has not yet been reported [6].

References