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Gene Review

dpy-10  -  Protein DPY-10

Caenorhabditis elegans

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High impact information on dpy-10

  • Reduction-of-function mutations in two Caenorhabditis elegans genes, the receptor tyrosine kinase gene let-23 and the collagen gene dpy-10, both alter the AG at the end of a short (ca. 50-nucleotide) intron to AA [1].
  • The genes do not, however, appear to be functionally redundant, because a dpy-10 null mutant is not rescued by the dpy-2 gene [2].
  • The nature of this mutation, combined with genetic data, indicates that DLRol is the null phenotype of dpy-10 [2].

Anatomical context of dpy-10


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