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Gene Review

col-2  -  Protein COL-2

Caenorhabditis elegans

 
 
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High impact information on col-2

 

Biological context of col-2

  • The complete nucleotide sequences of two of these genes, col-1 and col-2, have been determined [1].
  • The C. elegans genome contains 50 or more collagen genes, the majority of which probably encode cuticle collagens; col-1 and col-2 apparently are members of this large family of cuticle collagen genes [1].
 

Other interactions of col-2

  • These collagen polypeptides, as well as those encoded by the previously sequenced C. elegans collagen genes col-1 and col-2, share a common organization into five domains: an amino-terminal leader, a short (30-33 aa) (Gly-X-Y)n domain, a non(Gly-X-Y) spacer, a long (127-132 aa) (Gly-X-Y)n domain, and a short carboxyl-terminal domain [3].

References

 
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