The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Oc90  -  otoconin 90

Mus musculus

Synonyms: Oc95, Ocn-95, Onc-95, Otoconin-90, Otoconin-95, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Oc90


High impact information on Oc90


Biological context of Oc90

  • Otoconin-90, the principal otoconial matrix protein, provided a tool to investigate the molecular mechanism of otoconial morphogenesis [5].

Anatomical context of Oc90


Associations of Oc90 with chemical compounds

  • Because of ample expression of otoconin-90 protein in the absence of the corresponding mRNA, we conclude that the luminal otoconin-90 is imported via longitudinal flow from the vestibular compartments, where both mRNA and protein are strongly expressed [5].


  1. Genomic structure and evolution of a novel gene (PLA2L) with duplicated phospholipase A2-like domains. Kowalski, P.E., Freeman, J.D., Nelson, D.T., Mager, D.L. Genomics (1997) [Pubmed]
  2. Characterization of otoconin-95, the major protein of murine otoconia, provides insights into the formation of these inner ear biominerals. Verpy, E., Leibovici, M., Petit, C. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  3. Mapping the mouse otoconin-90 (Oc90) gene to chromosome 15. Wang, Y., Thalmann, I., Thalmann, R., Ornitz, D.M. Genomics (1999) [Pubmed]
  4. X-ray-induced deletion complexes in embryonic stem cells on mouse chromosome 15. Chick, W.S., Mentzer, S.E., Carpenter, D.A., Rinchik, E.M., Johnson, D., You, Y. Mamm. Genome (2005) [Pubmed]
  5. Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice. Ignatova, E.G., Thalmann, I., Xu, B., Ornitz, D.M., Thalmann, R. Hear. Res. (2004) [Pubmed]
WikiGenes - Universities