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Gene Review

Rps3a1  -  ribosomal protein S3A1

Mus musculus

Synonyms: 40S ribosomal protein S3a, Protein TU-11, Rps3a
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High impact information on Rps3a


Biological context of Rps3a

  • Rps3a and Fos could thus be effectors of the transformed phenotype [4].
  • The immune serum against the parasite 66kDa polypeptide when used to screen a L. major cDNA library could identify clones encoding for the human v-fos transformation effector homologue, namely ribosomal protein S3a, and thus was named LmS3a-related protein (LmS3arp) [5].


  1. Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosis. Naora, H., Takai, I., Adachi, M., Naora, H. J. Cell Biol. (1998) [Pubmed]
  2. Altered gene expression in liver from a murine model of hyperhomocysteinemia. Robert, K., Chassé, J.F., Santiard-Baron, D., Vayssettes, C., Chabli, A., Aupetit, J., Maeda, N., Kamoun, P., London, J., Janel, N. J. Biol. Chem. (2003) [Pubmed]
  3. Dual role of the Leishmania major ribosomal protein S3a homologue in regulation of T- and B-cell activation. Cordeiro-Da-Silva, A., Borges, M.C., Guilvard, E., Ouaissi, A. Infect. Immun. (2001) [Pubmed]
  4. The S3a ribosomal protein gene is identical to the Fte-1 (v-fos transformation effector) gene and the TNF-alpha-induced TU-11 gene, and its transcript level is altered in transformed and tumor cells. Lecomte, F., Szpirer, J., Szpirer, C. Gene (1997) [Pubmed]
  5. Cloning of a Leishmania major gene encoding for an antigen with extensive homology to ribosomal protein S3a. Zemzoumi, K., Guilvard, E., Sereno, D., Preto, A., Benlemlih, M., Da Silva, A.C., Lemesre, J.L., Ouaissi, A. Gene (1999) [Pubmed]
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