The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

TRIM35  -  tripartite motif containing 35

Homo sapiens

Synonyms: HLS5, Hemopoietic lineage switch protein 5, KIAA1098, MAIR, Tripartite motif-containing protein 35
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of TRIM35

  • The acidification patterns were not adequate to differentiate Bifidobacterium species, as determined previously by Mitsuoka (Bifidobacteria Microflora 3:11-28, 1984) and Scardovi (p. 1418-1434, in P. H. A. Sneath, N. S. Mair, M. E. Sharpe, and J. G. Holt, ed., Bergey's Manual of Systematic Bacteriology, vol. 2, 1986) [1].

Psychiatry related information on TRIM35

  • Two cases of diencephalic amnesia are summarized in particular (cases of Mair et al., 1979) as they have received extensive neuropsychological and neuropathological investigation [2].
  • Only clonidine had a significant effect on measures of anterograde amnesia, and this response was restricted to the same psychometric measures that improved with clonidine in an earlier study (McEntee and Mair 1980) [3].
  • Finally, several authors (e.g., Bruner, 1986; Howard, 1989; Mair, 1989; McAdams, 1985; Polkinghorne, 1988; Sarbin, 1986) see the development of identity as an issue of life-story construction; psychopathology as instances of life stories gone awry; and psychotherapy as exercises in story repair [4].

High impact information on TRIM35

  • An activating receptor, myeloid-associated Ig-like receptor (MAIR) II, is expressed on a subset of B cells and macrophages in the spleen and peritoneal cavity of mice and associates with DAP12 in these cells [5].
  • Improvement of the Mair scoring system using structural equations modeling for classifying the diagnostic adequacy of cytology material from thyroid lesions [6].

Analytical, diagnostic and therapeutic context of TRIM35

  • Using data on fine-needle biopsies of 200 thyroid lesions by both fine-needle aspiration (FNA) and fine-needle capillary sampling (FNC), we demonstrate that our modification of the Mair scoring system is more sensitive and more consistent with the structural equations model [6].


  1. Phenotypic differentiation of bifidobacteria of human and animal origins. Gavini, F., Pourcher, A.M., Neut, C., Monget, D., Romond, C., Oger, C., Izard, D. Int. J. Syst. Bacteriol. (1991) [Pubmed]
  2. The neuropathology of amnesia. Markowitsch, H.J., Pritzel, M. Prog. Neurobiol. (1985) [Pubmed]
  3. Cognitive enhancement in Korsakoff's psychosis by clonidine: a comparison with L-dopa and ephedrine. Mair, R.G., McEntee, W.J. Psychopharmacology (Berl.) (1986) [Pubmed]
  4. Culture tales. A narrative approach to thinking, cross-cultural psychology, and psychotherapy. Howard, G.S. The American psychologist. (1991) [Pubmed]
  5. Dual Assemblies of an Activating Immune Receptor, MAIR-II, with ITAM-Bearing Adapters DAP12 and FcR{gamma} Chain on Peritoneal Macrophages. Nakahashi, C., Tahara-Hanaoka, S., Totsuka, N., Okoshi, Y., Takai, T., Ohkohchi, N., Honda, S., Shibuya, K., Shibuya, A. J. Immunol. (2007) [Pubmed]
  6. Improvement of the Mair scoring system using structural equations modeling for classifying the diagnostic adequacy of cytology material from thyroid lesions. Kulkarni, H.R., Kamal, M.M., Arjune, D.G. Diagn. Cytopathol. (1999) [Pubmed]
WikiGenes - Universities