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MeSH Review

Amnesia, Anterograde

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Disease relevance of Amnesia, Anterograde


Psychiatry related information on Amnesia, Anterograde


High impact information on Amnesia, Anterograde

  • BACKGROUND: Alcohol-induced blackouts (ie, periods of anterograde amnesia) have received limited recent research attention [9].
  • Basolateral amygdala lesions block diazepam-induced anterograde amnesia in an inhibitory avoidance task [10].
  • We investigated the efficacy of the intracarotid amobarbital procedure to accurately predict post-temporal lobectomy anterograde amnesia [11].
  • Both ECS-induced MCR subsensitivity and a clinically equivalent model of ECT-induced anterograde amnesia were not demonstrable after a single ECS, were cumulatively induced by repeated treatments, and may be reversible by administration concurrently with ECS of a muscarinic antagonist [12].
  • These results indicate that (1). a functional 5-HT(1A) receptor antagonism can attenuate the anterograde amnesia produced by muscarinic-receptor blockade, and (2). the AChE inhibitors tacrine and donepezil differ in their ability to modify muscarinic-receptor-mediated function in vivo [13].

Chemical compound and disease context of Amnesia, Anterograde


Anatomical context of Amnesia, Anterograde


Gene context of Amnesia, Anterograde

  • Antisense 'knockdowns' of M1 receptors induces transient anterograde amnesia in mice [21].
  • 5-HT1A receptor agonists induce anterograde amnesia in mice through a postsynaptic mechanism [22].
  • On the hypothesis that anterograde amnesia for episodic memory involves a deficit in contextual memory, amnesic subjects should confuse familiarity with distractor items gained during Test 1 with familiarity gained during original list presentation [23].
  • The role of the hippocampal system in retrograde and anterograde amnesia was investigated by using a novel olfactory-guided paradigm and a traditional test of spatial learning [24].

Analytical, diagnostic and therapeutic context of Amnesia, Anterograde


  1. Interactions of neurotoxins with non-NMDA glutamate receptors: an autoradiographic study. Künig, G., Niedermeyer, B., Krause, F., Hartmann, J., Deckert, J., Ransmayr, G., Heinsen, H., Beckmann, H., Riederer, P. J. Neural Transm. Suppl. (1994) [Pubmed]
  2. A comparative study of intravenous diazepam and midazolam for oral surgery. Clark, R.N., Rodrigo, M.R. J. Oral Maxillofac. Surg. (1986) [Pubmed]
  3. Effect of flunitrazepam (Rohypnol) on awareness during anaesthesia for caesarean section. Soyannwo, O.A., Elegbe, E.O., Odugbesan, C.O. African journal of medicine and medical sciences. (1988) [Pubmed]
  4. Metamemory without the memory: are people aware of midazolam-induced amnesia? Merritt, P., Hirshman, E., Hsu, J., Berrigan, M. Psychopharmacology (Berl.) (2005) [Pubmed]
  5. Cognitive enhancement in Korsakoff's psychosis by clonidine: a comparison with L-dopa and ephedrine. Mair, R.G., McEntee, W.J. Psychopharmacology (Berl.) (1986) [Pubmed]
  6. NMDA processes mediate anterograde amnesia of contextual fear conditioning induced by hippocampal damage: immunization against amnesia by context preexposure. Young, S.L., Bohenek, D.L., Fanselow, M.S. Behav. Neurosci. (1994) [Pubmed]
  7. The effects of estazolam on sleep, performance, and memory: a long-term sleep laboratory study of elderly insomniacs. Vogel, G.W., Morris, D. Journal of clinical pharmacology. (1992) [Pubmed]
  8. Pharmacological characterization of 6-bromo-3'-nitroflavone, a synthetic flavonoid with high affinity for the benzodiazepine receptors. Wolfman, C., Viola, H., Marder, M., Ardenghi, P., Wasowski, C., Schröder, N., Izquierdo, I., Rúveda, E., Paladini, A., Medina, J.H. Pharmacol. Biochem. Behav. (1998) [Pubmed]
  9. Genetic epidemiology of alcohol-induced blackouts. Nelson, E.C., Heath, A.C., Bucholz, K.K., Madden, P.A., Fu, Q., Knopik, V., Lynskey, M.T., Lynskey, M.T., Whitfield, J.B., Statham, D.J., Martin, N.G. Arch. Gen. Psychiatry (2004) [Pubmed]
  10. Basolateral amygdala lesions block diazepam-induced anterograde amnesia in an inhibitory avoidance task. Tomaz, C., Dickinson-Anson, H., McGaugh, J.L. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  11. The intracarotid amobarbital procedure as a predictor of memory failure following unilateral temporal lobectomy. Loring, D.W., Lee, G.P., Meador, K.J., Flanigin, H.F., Smith, J.R., Figueroa, R.E., Martin, R.C. Neurology (1990) [Pubmed]
  12. Studies on the role of brain cholinergic systems in the therapeutic mechanisms and adverse effects of ECT and lithium. Lerer, B. Biol. Psychiatry (1985) [Pubmed]
  13. Selective 5-HT1A antagonists WAY 100635 and NAD-299 attenuate the impairment of passive avoidance caused by scopolamine in the rat. Misane, I., Ogren, S.O. Neuropsychopharmacology (2003) [Pubmed]
  14. Disinhibition, amnestic reactions, and other adverse reactions secondary to triazolam: a review of the literature. Rothschild, A.J. The Journal of clinical psychiatry. (1992) [Pubmed]
  15. Anterograde amnesia with oral lorazepam. Mac, D.S., Kumar, R., Goodwin, D.W. The Journal of clinical psychiatry. (1985) [Pubmed]
  16. Clinical pharmacokinetics and pharmacodynamics of zolpidem. Therapeutic implications. Salvà, P., Costa, J. Clinical pharmacokinetics. (1995) [Pubmed]
  17. Comparative anterograde amnestic and anticonvulsant effects of two types of NMDA receptor antagonists: MK-801 and HA-966. Xu, X., Klinger, P., Davis, R. Psychopharmacology (Berl.) (1995) [Pubmed]
  18. Nefiracetam prevents propofol-induced anterograde and retrograde amnesia in the rodent without compromising quality of anesthesia. O'Gorman, D.A., O'Connell, A.W., Murphy, K.J., Moriarty, D.C., Shiotani, T., Regan, C.M. Anesthesiology (1998) [Pubmed]
  19. The ventral hippocampus and fear conditioning in rats. Different anterograde amnesias of fear after tetrodotoxin inactivation and infusion of the GABA(A) agonist muscimol. Bast, T., Zhang, W.N., Feldon, J. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (2001) [Pubmed]
  20. Studies on retrograde and anterograde amnesia of olfactory memory after denervation of the hippocampus by entorhinal cortex lesions. Staubli, U., Fraser, D., Kessler, M., Lynch, G. Behavioral and neural biology. (1986) [Pubmed]
  21. Antisense 'knockdowns' of M1 receptors induces transient anterograde amnesia in mice. Ghelardini, C., Galeotti, N., Matucci, R., Bellucci, C., Gualtieri, F., Capaccioli, S., Quattrone, A., Bartolini, A. Neuropharmacology (1999) [Pubmed]
  22. 5-HT1A receptor agonists induce anterograde amnesia in mice through a postsynaptic mechanism. Mendelson, S.D., Quartermain, D., Francisco, T., Shemer, A. Eur. J. Pharmacol. (1993) [Pubmed]
  23. The effects of repeating a recognition test in lorazepam-induced amnesia: evidence for impaired contextual memory as a cause of amnesia. Brown, J., Brown, M.W. The Quarterly journal of experimental psychology. A, Human experimental psychology. (1990) [Pubmed]
  24. The effects of lesions to the rat hippocampus or rhinal cortex on olfactory and spatial memory: retrograde and anterograde findings. Kaut, K.P., Bunsey, M.D. Cognitive, affective & behavioral neuroscience. (2001) [Pubmed]
  25. Comparative study of midazolam and diazepam in premedication of bronchoscopy. Kolek, V., Jezdinský, J. Acta Universitatis Palackianae Olomucensis Facultatis Medicae. (1991) [Pubmed]
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