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Gene Review

MGA  -  MGA, MAX dimerization protein

Homo sapiens

Synonyms: FLJ12634, KIAA0518, MAD5, MAX dimerization protein 5, MAX gene-associated protein, ...
 
 
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Disease relevance of MGA

 

High impact information on MGA

  • In Experiment 2, the number of heifers conceiving to AI following the MGA/PG estrous synchronization regimen was increased by mass insemination of all heifers not exhibiting estrus by 72 h after PG [2].
  • Two experiments were conducted to determine the conception rates of heifers time-inseminated following melengestrol acetate/prostaglandin F(2alpha) (MGA/PG) estrous synchronization treatment [2].
  • Estrus was synchronized with either a progestin compound (MGA) or by the use of a luteolytic agent (PGF) [3].
  • Collectively, these trials do not provide strong support for a single injection of FSH, as used here, nor does it indicate a clear advantage for either MGA or PGF as a means of enhancing the ovulation rate or embryo quality [3].
 

Biological context of MGA

  • In cyclic heifers, timed insemination can increase the percentage of heifers pregnant after being synchronized with MGA/PG [2].
 

Analytical, diagnostic and therapeutic context of MGA

References

  1. DDBJ working on evaluation and classification of bacterial genes in INSDC. Sugawara, H., Abe, T., Gojobori, T., Tateno, Y. Nucleic Acids Res. (2007) [Pubmed]
  2. Synchronization of estrus in yearling beef heifers with the melengestrol acetate/prostaglandin F(2alpha) system: Efficiency of timed insemination 72 hours after prostaglandin treatment. Larson, R.L., Corah, L.R., Peters, C.W. Theriogenology (1996) [Pubmed]
  3. The effect of estrus synchronization scheme, injection protocol and large ovarian follicle on response to superovulation in beef heifers. Staigmiller, R.B., Macneil, M.D., Bellows, R.A., Short, R.E., Phelps, D.A. Theriogenology (1995) [Pubmed]
  4. Comparison of two MGA-PGF(2)alpha systems for synchronization of estrus in beef heifers. Mauck, H.S., King, M.E., Holland, M.D., Lefever, D.G., Odde, K.G. Theriogenology (1994) [Pubmed]
 
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