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Gene Review

SSBP3  -  single stranded DNA binding protein 3

Homo sapiens

Synonyms: CSDP, FLJ10355, SSDP, SSDP1, Sequence-specific single-stranded-DNA-binding protein, ...
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Disease relevance of SSBP3


High impact information on SSBP3


Biological context of SSBP3

  • RAPD typing of the isolates revealed 10 different genotypes, whereas nine genotypes were identified by SSDP [8].

Associations of SSBP3 with chemical compounds

  • SSDP decreased from 100 to 89 mm Hg in the fosinopril group (p < 0.01) and from 100 to 92 mm Hg in the enalapril group (p < 0.01) [9].

Analytical, diagnostic and therapeutic context of SSBP3

  • The pairs of five sequence-specific DNA primers (SSDP), characteristic of the 5' and 3' extremities of the RAPD products, were then used in high stringency PCR to type 43 clinical strains of A. fumigatus from 13 patients, according to the presence or absence of a single amplified band [10].


  1. Association of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition element. Johnson, E.M., Chen, P.L., Krachmarov, C.P., Barr, S.M., Kanovsky, M., Ma, Z.W., Lee, W.H. J. Biol. Chem. (1995) [Pubmed]
  2. Evidence that replication of human neurotropic JC virus DNA in glial cells is regulated by the sequence-specific single-stranded DNA-binding protein Pur alpha. Chang, C.F., Gallia, G.L., Muralidharan, V., Chen, N.N., Zoltick, P., Johnson, E., Khalili, K. J. Virol. (1996) [Pubmed]
  3. A single-stranded DNA-binding protein from Crithidia fasciculata recognizes the nucleotide sequence at the origin of replication of kinetoplast DNA minicircles. Tzfati, Y., Abeliovich, H., Kapeller, I., Shlomai, J. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  4. Association of Pur alpha and E2F-1 suppresses transcriptional activity of E2F-1. Darbinian, N., Gallia, G.L., Kundu, M., Shcherbik, N., Tretiakova, A., Giordano, A., Khalili, K. Oncogene (1999) [Pubmed]
  5. A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity. Castro, P., Liang, H., Liang, J.C., Nagarajan, L. Genomics (2002) [Pubmed]
  6. Self-association of Puralpha is mediated by RNA. Gallia, G.L., Darbinian, N., Johnson, E.M., Khalili, K. J. Cell. Biochem. (1999) [Pubmed]
  7. Enantioresolution of fluorinated diphenylmethanols and determination of their absolute configurations by X-Ray crystallographic and 1H NMR anisotropy methods. Naito, J., Kosaka, M., Sugito, T., Watanabe, M., Harada, N., Pirkle, W.H. Chirality. (2004) [Pubmed]
  8. Molecular epidemiology of airway colonisation by Aspergillus fumigatus in cystic fibrosis patients. Cimon, B., Symoens, F., Zouhair, R., Chabasse, D., Nolard, N., Defontaine, A., Bouchara, J.P. J. Med. Microbiol. (2001) [Pubmed]
  9. Fosinopril versus enalapril in the treatment of hypertension: a double-blind study in 195 patients. Hansson, L., Forslund, T., Höglund, C., Istad, H., Lederballe-Pedersen, O., Kristinsson, A., Segaard, E., Svensson, A., Aärynen, M., Wahrenberg, H., Wennersten, G., Kjellström, T. J. Cardiovasc. Pharmacol. (1996) [Pubmed]
  10. Molecular typing of Aspergillus fumigatus strains by sequence-specific DNA primer (SSDP) analysis. Mondon, P., Brenier, M.P., Symoens, F., Rodriguez, E., Coursange, E., Chaib, F., Lebeau, B., Piens, M.A., Tortorano, A.M., Mallié, M., Chapuis, F., Carlotti, A., Villard, J., Viviani, M.A., Nolard, N., Bastide, J.M., Ambroise-Thomas, P., Grillot, R. FEMS Immunol. Med. Microbiol. (1997) [Pubmed]
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