Gene Review:
blaR1 - BlaR1
Staphylococcus aureus
- Discrete steps in sensing of beta-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium. Thumanu, K., Cha, J., Fisher, J.F., Perrins, R., Mobashery, S., Wharton, C. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus. Wilke, M.S., Hills, T.L., Zhang, H.Z., Chambers, H.F., Strynadka, N.C. J. Biol. Chem. (2004)
- Resistance to beta-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus. Golemi-Kotra, D., Cha, J.Y., Meroueh, S.O., Vakulenko, S.B., Mobashery, S. J. Biol. Chem. (2003)
- Lysine N(zeta)-Decarboxylation in the BlaR1 Protein from Staphylococcus aureus at the Root of Its Function As an Antibiotic Sensor. Cha, J., Mobashery, S. J. Am. Chem. Soc. (2007)
- Crystal structure of the sensor domain of the BlaR penicillin receptor from Bacillus licheniformis. Kerff, F., Charlier, P., Colombo, M.L., Sauvage, E., Brans, A., Frère, J.M., Joris, B., Fonzé, E. Biochemistry (2003)
- Regulation of beta-lactamase synthesis as a novel site of action for suppression of methicillin resistance in Staphylococcus aureus. Bruns, O., Bruns, W., Pulverer, G. Zentralbl. Bakteriol. (1997)