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Gene Review

CACYBP  -  calcyclin binding protein

Homo sapiens

Synonyms: CacyBP, Calcyclin-binding protein, GIG5, PNAS-107, S100A6-binding protein, ...
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Disease relevance of CACYBP


High impact information on CACYBP


Biological context of CACYBP


Associations of CACYBP with chemical compounds

  • In the RA-induced differentiated SH-SY5Y cells, CacyBP was phosphorylated on serine residue(s), while it existed in a dephosphorylated form in normal (uninduced) cells [1].
  • BALB/c mouse splenocytes were immunized with purified 6 x His-CacyBP fusion protein and fused with myeloma cells using polyethylene glycol (PEG) 4000 [4].

Other interactions of CACYBP


Analytical, diagnostic and therapeutic context of CACYBP


  1. Translocation and phosphorylation of calcyclin binding protein during retinoic acid-induced neuronal differentiation of neuroblastoma SH-SY5Y cells. Wu, J., Tan, X., Peng, X., Yuan, J., Qiang, B. J. Biochem. Mol. Biol. (2003) [Pubmed]
  2. S100A6 and CacyBP/SIP - two proteins discovered in ehrlich ascites tumor cells that are potentially involved in the degradation of beta-catenin. Filipek, A. Chemotherapy. (2006) [Pubmed]
  3. Calcyclin binding protein promotes DNA synthesis and differentiation in rat neonatal cardiomyocytes. Au, K.W., Kou, C.Y., Woo, A.Y., Chim, S.S., Fung, K.P., Cheng, C.H., Waye, M.M., Tsui, S.K. J. Cell. Biochem. (2006) [Pubmed]
  4. Establishment and characterization of calcyclin binding protein (CacyBP) monoclonal antibody. Zhai, H., Shi, Y., Yu, J., Hong, L., Tang, H., Wang, J., Hu, S., Bai, F., Fan, D. Hybridoma (2005) (2006) [Pubmed]
  5. Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP). Matsuzawa, S., Li, C., Ni, C.Z., Takayama, S., Reed, J.C., Ely, K.R. J. Biol. Chem. (2003) [Pubmed]
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