The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

ARHGEF16  -  Rho guanine nucleotide exchange factor...

Homo sapiens

Synonyms: EPHEXIN4, Ephexin-4, GEF16, NBR, Rho guanine nucleotide exchange factor 16
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on ARHGEF16

  • This proposed mechanism has been supported by additional information, including negative genotoxicity tests for d-limonene and its oxide metabolites, experimentally verified tumor promotion, and enhanced cell proliferation primarily in P2 segment tubule cells in male F344 rats, but no such effects in the alpha 2U-g-deficient NBR rat [1].
  • Type I hair cells were identified morphologically based on the ratios of neck width to cuticular plate width (NPR < 0.72) as well as neck width to cell body width (NBR < 0.64) [2].
  • A new concept emerging is that study of steady-state mechanical parameters such as maximal isometric force (Po) velocity is inadequate because two types of crossbridges (normally cycling (NBR) and latch) seem to be sequentially active during smooth muscle contraction [3].
  • 1998 should prove to be a milestone year for the ABA, with the development of Version 2 of the NATIONAL TRACS/ABA Burn Registry software and the expansion of the NBR [4].
  • Blockade of the peroneal nerve eliminated both PBR and NBR on the dorsal foot.(ABSTRACT TRUNCATED AT 250 WORDS)[5]
 

Anatomical context of ARHGEF16

  • In 4-h 51Cr release assays, splenic NK cells from FH rats killed YAC-1, RL male l and G1-TC tumor targets without deficiency based upon comparison with cells from BD-IV, BD-IX and NBR inbred rat strains [6].

References

  1. Risk assessment of d-limonene: an example of male rat-specific renal tumorigens. Hard, G.C., Whysner, J. Crit. Rev. Toxicol. (1994) [Pubmed]
  2. The delayed rectifier, IKI, is the major conductance in type I vestibular hair cells across vestibular end organs. Ricci, A.J., Rennie, K.J., Correia, M.J. Pflugers Arch. (1996) [Pubmed]
  3. The biophysics and biochemistry of smooth muscle contraction. Stephens, N.L., Seow, C.Y., Halayko, A.J., Jiang, H. Can. J. Physiol. Pharmacol. (1992) [Pubmed]
  4. Progress report: 1998 NATIONAL TRACS/ABA Burn Registry and related activities. McDonald-Smith, G.P. The Journal of burn care & rehabilitation. (1998) [Pubmed]
  5. Cutaneous vasodilatation responses synchronize with sweat expulsions. Sugenoya, J., Ogawa, T., Jmai, K., Ohnishi, N., Natsume, K. European journal of applied physiology and occupational physiology. (1995) [Pubmed]
  6. Natural killer cell activity in fawn-hooded rats. Starkey, J.R., Prieur, D.J., Ristow, S.S. Experientia (1983) [Pubmed]
 
WikiGenes - Universities