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Gene Review

Tgfbr1  -  transforming growth factor, beta receptor 1

Rattus norvegicus

Synonyms: Alk5, SKR4, Serine/threonine-protein kinase receptor R4, Skr4, TGF-beta receptor type I, ...
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High impact information on Tgfbr1


Anatomical context of Tgfbr1


Associations of Tgfbr1 with chemical compounds


Other interactions of Tgfbr1

  • It was concluded that the beneficial effects of retinoids on glomerular damage are presumably due to a marked reduction in renal TGF-beta 1 and TGF receptor II expression [2].

Analytical, diagnostic and therapeutic context of Tgfbr1


  1. Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines. Massagué, J., Like, B. J. Biol. Chem. (1985) [Pubmed]
  2. Effects of retinoids on the TGF-beta system and extracellular matrix in experimental glomerulonephritis. Morath, C., Dechow, C., Lehrke, I., Haxsen, V., Waldherr, R., Floege, J., Ritz, E., Wagner, J. J. Am. Soc. Nephrol. (2001) [Pubmed]
  3. Effect of substance P on gene expression of transforming growth factor beta-1 and its receptors in rat's fibroblasts. Lai, X.N., Wang, Z.G., Zhu, J.M., Wang, L.L. Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association. (2003) [Pubmed]
  4. Isotretinoin alleviates renal damage in rat chronic glomerulonephritis. Schaier, M., Lehrke, I., Schade, K., Morath, C., Shimizu, F., Kawachi, H., Grone, H.J., Ritz, E., Wagner, J. Kidney Int. (2001) [Pubmed]
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