Gene Review:
smg - smaug
Drosophila melanogaster
Synonyms:
CG5263, D69, Dmel\CG5263, Protein Smaug, SMG, ...
- smaug protein represses translation of unlocalized nanos mRNA in the Drosophila embryo. Smibert, C.A., Wilson, J.E., Kerr, K., Macdonald, P.M. Genes Dev. (1996)
- RNA recognition via the SAM domain of Smaug. Green, J.B., Gardner, C.D., Wharton, R.P., Aggarwal, A.K. Mol. Cell (2003)
- Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression. Nelson, M.R., Leidal, A.M., Smibert, C.A. EMBO J. (2004)
- The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators. Aviv, T., Lin, Z., Lau, S., Rendl, L.M., Sicheri, F., Smibert, C.A. Nat. Struct. Biol. (2003)
- Rapid ATP-dependent deadenylation of nanos mRNA in a cell-free system from Drosophila Embryos. Jeske, M., Meyer, S., Temme, C., Freudenreich, D., Wahle, E. J. Biol. Chem. (2006)
- Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. Semotok, J.L., Cooperstock, R.L., Pinder, B.D., Vari, H.K., Lipshitz, H.D., Smibert, C.A. Curr. Biol. (2005)
- Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro. Smibert, C.A., Lie, Y.S., Shillinglaw, W., Henzel, W.J., Macdonald, P.M. RNA (1999)
- Temporal complexity within a translational control element in the nanos mRNA. Forrest, K.M., Clark, I.E., Jain, R.A., Gavis, E.R. Development (2004)
- Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4. Zaessinger, S., Busseau, I., Simonelig, M. Development (2006)
- Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila. Dahanukar, A., Walker, J.A., Wharton, R.P. Mol. Cell (1999)
- Crystallization and characterization of Smaug: a novel RNA-binding motif. Green, J.B., Edwards, T.A., Trincao, J., Escalante, C.R., Wharton, R.P., Aggarwal, A.K. Biochem. Biophys. Res. Commun. (2002)