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Gene Review

ALB  -  albumin

Canis lupus familiaris

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Disease relevance of ALB

  • An animal model was used to assess the efficacy of levofloxacin (LVFX) incorporated into albumin (ALB)-sealed Dacron (LVFX-ALB) graft for the prevention of vascular graft infections caused by Staphylococcus aureus [1].
  • Body weight, TP, ALB, and BUN were identified as prognostic indicators for short-term outcome [2].
  • Following trauma and hypotension (MAP 40 mmHg; 3.0 +/- 0.5 hr) the animals were randomized to treatment with autologous blood and hydroxyethyl starch 6% (HES 450/0.7), or human serum albumin 5% (ALB), dextran-60 6% (DX), Ringer's lactate (RL), and hyperosmolar saline 1.3% (HS), respectively [3].

High impact information on ALB


Analytical, diagnostic and therapeutic context of ALB

  • We have developed novel PCR markers representing three dog genes (ALB, FOS, HNRPA2B1) for which no sequence or mapping data were previously available, to our knowledge [6].


  1. Prophylaxis of local vascular graft infection with levofloxacin incorporated into albumin-sealed dacron graft (LVFX-ALB Graft). Osada, T., Yamamura, K., Fujimoto, K., Mizuno, K., Sakurai, T., Ohta, M., Nabeshima, T. Microbiol. Immunol. (1999) [Pubmed]
  2. Survival and prognostic indicators for dogs with intrahepatic portosystemic shunts: 32 cases (1990-2000). Papazoglou, L.G., Monnet, E., Seim, H.B. Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons. (2002) [Pubmed]
  3. Long-term observation following traumatic-hemorrhagic shock in the dog: a comparison of crystalloidal vs. colloidal fluids. Hein, L.G., Albrecht, M., Dworschak, M., Frey, L., Brückner, U.B. Circ. Shock (1988) [Pubmed]
  4. A simple method to measure mesenteric arteriovenous shunt flow during arteriography. Barth, K.H., Mitchell, T.G., Groves, T.F., Starr, F.L., Kasecamp, W.R., White, R.I. Investigative radiology. (1978) [Pubmed]
  5. Disease-induced alterations in plasma drug-binding proteins and their influence on drug binding percentages in dogs. Ikenoue, N., Saitsu, Y., Shimoda, M., Kokue, E. The Veterinary quarterly. (2000) [Pubmed]
  6. Chromosome assignment of six dog genes by FISH, and correlation with dog-human Zoo-FISH data. Thomas, R., Breen, M., Binns, M.M. Anim. Genet. (2001) [Pubmed]
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