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ADORA2A  -  adenosine A2a receptor

Canis lupus familiaris

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High impact information on ADORA2A


Biological context of ADORA2A


Anatomical context of ADORA2A


Associations of ADORA2A with chemical compounds

  • DMPX (5-50 nmol/kg), a weak adenosine A2A receptor antagonist, caused a progressive parallel shift to the right in the dose response curve for CGS21680-induced pancreatic secretion without changes in the maximal response [4].


  1. Pharmacological stress thallium scintigraphy with 2-cyclohexylmethylidenehydrazinoadenosine (WRC-0470). A novel, short-acting adenosine A2A receptor agonist. Glover, D.K., Ruiz, M., Yang, J.Y., Koplan, B.A., Allen, T.R., Smith, W.H., Watson, D.D., Barrett, R.J., Beller, G.A. Circulation (1996) [Pubmed]
  2. Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2A receptor agonist, in reperfused canine myocardium. Glover, D.K., Riou, L.M., Ruiz, M., Sullivan, G.W., Linden, J., Rieger, J.M., Macdonald, T.L., Watson, D.D., Beller, G.A. Am. J. Physiol. Heart Circ. Physiol. (2005) [Pubmed]
  3. Adenosine attenuates reperfusion-induced apoptotic cell death by modulating expression of Bcl-2 and Bax proteins. Zhao, Z.Q., Budde, J.M., Morris, C., Wang, N.P., Velez, D.A., Muraki, S., Guyton, R.A., Vinten-Johansen, J. J. Mol. Cell. Cardiol. (2001) [Pubmed]
  4. Subtypes of adenosine receptors on pancreatic exocrine secretion in anaesthetized dogs. Iwatsuki, K. Fundamental & clinical pharmacology. (2000) [Pubmed]
  5. Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells. Dasgupta, S., Ferré, S., Kull, B., Hedlund, P.B., Finnman, U.B., Ahlberg, S., Arenas, E., Fredholm, B.B., Fuxe, K. Eur. J. Pharmacol. (1996) [Pubmed]
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