Gene Review:
mbc - myoblast city
Drosophila melanogaster
Synonyms:
CG10379, DOCK180, Dm MBC, Dmel\CG10379, Dock180, ...
- Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Nolan, K.M., Barrett, K., Lu, Y., Hu, K.Q., Vincent, S., Settleman, J. Genes Dev. (1998)
- Presynaptic development at the Drosophila neuromuscular junction: assembly and localization of presynaptic active zones. Prokop, A., Landgraf, M., Rushton, E., Broadie, K., Bate, M. Neuron (1996)
- DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis. Kunisaki, Y., Nishikimi, A., Tanaka, Y., Takii, R., Noda, M., Inayoshi, A., Watanabe, K., Sanematsu, F., Sasazuki, T., Sasaki, T., Fukui, Y. J. Cell Biol. (2006)
- PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis. Ishimaru, S., Ueda, R., Hinohara, Y., Ohtani, M., Hanafusa, H. EMBO J. (2004)
- In Drosophila melanogaster, the Rolling pebbles isoform 6 (Rols6) is essential for proper Malpighian tubule morphology. Pütz, M., Kesper, D.A., Buttgereit, D., Renkawitz-Pohl, R. Mech. Dev. (2005)
- Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development. Rushton, E., Drysdale, R., Abmayr, S.M., Michelson, A.M., Bate, M. Development (1995)
- Essential genes for myoblast fusion in Drosophila embryogenesis. Paululat, A., Holz, A., Renkawitz-Pohl, R. Mech. Dev. (1999)
- Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization. Erickson, M.R., Galletta, B.J., Abmayr, S.M. J. Cell Biol. (1997)
- Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila. Chen, E.H., Olson, E.N. Dev. Cell (2001)
- Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC. Galletta, B.J., Niu, X.P., Erickson, M.R., Abmayr, S.M. Gene (1999)