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Gene Review

NCAM2  -  neural cell adhesion molecule 2

Homo sapiens

Synonyms: MGC51008, N-CAM-2, NCAM-2, NCAM21, Neural cell adhesion molecule 2
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Disease relevance of NCAM2


High impact information on NCAM2


Biological context of NCAM2


Anatomical context of NCAM2


Other interactions of NCAM2

  • Unlike known STAT5 binding sites, this site is found within a very large intron and resides approximately 200 kb from the first coding exon of NCAM2 [3].


  1. Cloning of a novel human neural cell adhesion molecule gene (NCAM2) that maps to chromosome region 21q21 and is potentially involved in Down syndrome. Paoloni-Giacobino, A., Chen, H., Antonarakis, S.E. Genomics (1997) [Pubmed]
  2. Differential function of RNCAM isoforms in precise target selection of olfactory sensory neurons. Alenius, M., Bohm, S. Development (2003) [Pubmed]
  3. Identification of human STAT5-dependent gene regulatory elements based on interspecies homology. Nelson, E.A., Walker, S.R., Li, W., Liu, X.S., Frank, D.A. J. Biol. Chem. (2006) [Pubmed]
  4. A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity. Buckland, P.R., Coleman, S.L., Hoogendoorn, B., Guy, C., Smith, S.K., O'Donovan, M.C. Gene Expr. (2004) [Pubmed]
  5. A 2-Mb sequence-ready contig map and a novel immunoglobulin superfamily gene IGSF4 in the LOH region of chromosome 11q23.2. Gomyo, H., Arai, Y., Tanigami, A., Murakami, Y., Hattori, M., Hosoda, F., Arai, K., Aikawa, Y., Tsuda, H., Hirohashi, S., Asakawa, S., Shimizu, N., Soeda, E., Sakaki, Y., Ohki, M. Genomics (1999) [Pubmed]
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