Gene Review:
NKX6-1 - NK6 homeobox 1
Homo sapiens
Synonyms:
Homeobox protein NK-6 homolog A, Homeobox protein Nkx-6.1, NKX6.1, NKX6A, Nkx6.1
- Zebrafish and fly Nkx6 proteins have similar CNS expression patterns and regulate motoneuron formation. Cheesman, S.E., Layden, M.J., Von Ohlen, T., Doe, C.Q., Eisen, J.S. Development (2004)
- Peroxisome Proliferator-Activated Receptor-{gamma} Regulates Expression of PDX-1 and NKX6.1 in INS-1 Cells. Moibi, J.A., Gupta, D., Jetton, T.L., Peshavaria, M., Desai, R., Leahy, J.L. Diabetes (2007)
- Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1. Watada, H., Mirmira, R.G., Leung, J., German, M.S. J. Biol. Chem. (2000)
- The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Iype, T., Taylor, D.G., Ziesmann, S.M., Garmey, J.C., Watada, H., Mirmira, R.G. Mol. Endocrinol. (2004)
- Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently. Street, C.N., Lakey, J.R., Rajotte, R.V., Shapiro, A.M., Kieffer, T.J., Lyon, J.G., Kin, T., Korbutt, G.S. The review of diabetic studies : RDS (2004)
- Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro. Moriscot, C., de Fraipont, F., Richard, M.J., Marchand, M., Savatier, P., Bosco, D., Favrot, M., Benhamou, P.Y. Stem Cells (2005)
- Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1. Jørgensen, M.C., Vestergård Petersen, H., Ericson, J., Madsen, O.D., Serup, P. FEBS Lett. (1999)
- Isolation, characterization, and chromosomal mapping of the human Nkx6.1 gene (NKX6A), a new pancreatic islet homeobox gene. Inoue, H., Rudnick, A., German, M.S., Veile, R., Donis-Keller, H., Permutt, M.A. Genomics (1997)
- Developmental Biology of the Psammomys obesus Pancreas: Cloning and Expression of the Neurogenin-3 Gene. Vedtofte, L., B??dvarsd??ttir, T.B., Karlsen, A.E., Heller, R.S. J. Histochem. Cytochem. (2007)