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Gene Review

GPR84  -  G protein-coupled receptor 84

Homo sapiens

Synonyms: EX33, G-protein coupled receptor 84, GPCR4, Inflammation-related G-protein coupled receptor EX33
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Disease relevance of GPR84

  • The activation of GPR84 by medium-chain FFAs couples primarily to a pertussis toxin-sensitive G(i/o) pathway [1].

High impact information on GPR84


Anatomical context of GPR84


  1. Medium-chain Fatty Acids as Ligands for Orphan G Protein-coupled Receptor GPR84. Wang, J., Wu, X., Simonavicius, N., Tian, H., Ling, L. J. Biol. Chem. (2006) [Pubmed]
  2. Cloning and expression analysis of a novel G-protein-coupled receptor selectively expressed on granulocytes. Yousefi, S., Cooper, P.R., Potter, S.L., Mueck, B., Jarai, G. J. Leukoc. Biol. (2001) [Pubmed]
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