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Gene Review

MAGEL2  -  MAGE-like 2

Homo sapiens

Synonyms: MAGE-like protein 2, NDNL1, Necdin-like protein 1, PWLS, Protein nM15, ...
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Disease relevance of MAGEL2


High impact information on MAGEL2


Biological context of MAGEL2


Anatomical context of MAGEL2


Other interactions of MAGEL2


Analytical, diagnostic and therapeutic context of MAGEL2


  1. Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype. Lee, S., Kozlov, S., Hernandez, L., Chamberlain, S.J., Brannan, C.I., Stewart, C.L., Wevrick, R. Hum. Mol. Genet. (2000) [Pubmed]
  2. Evaluation of Prader-Willi Syndrome gene MAGEL2 in severe childhood-onset obesity. O'Neill, M.A., Farooqi, I.S., Wevrick, R. Obes. Res. (2005) [Pubmed]
  3. Temporal and parental-specific expression of imprinted genes in a newly derived Chinese human embryonic stem cell line and embryoid bodies. Sun, B.W., Yang, A.C., Feng, Y., Sun, Y.J., Zhu, Y., Zhang, Y., Jiang, H., Li, C.L., Gao, F.R., Zhang, Z.H., Wang, W.C., Kong, X.Y., Jin, G., Fu, S.J., Jin, Y. Hum. Mol. Genet. (2006) [Pubmed]
  4. Sequence-based design of single-copy genomic DNA probes for fluorescence in situ hybridization. Rogan, P.K., Cazcarro, P.M., Knoll, J.H. Genome Res. (2001) [Pubmed]
  5. Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor. Kuwako, K., Taniura, H., Yoshikawa, K. J. Biol. Chem. (2004) [Pubmed]
  6. Identification of a testis-specific gene (C15orf2) in the Prader-Willi syndrome region on chromosome 15. Färber, C., Gross, S., Neesen, J., Buiting, K., Horsthemke, B. Genomics (2000) [Pubmed]
  7. The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region. Boccaccio, I., Glatt-Deeley, H., Watrin, F., Roëckel, N., Lalande, M., Muscatelli, F. Hum. Mol. Genet. (1999) [Pubmed]
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