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Gene Review

CIAPIN1  -  cytokine induced apoptosis inhibitor 1

Homo sapiens

Synonyms: 2810413N20Rik, Anamorsin, CUA001, Cytokine-induced apoptosis inhibitor 1, DRE2, ...
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Disease relevance of CIAPIN1

  • Our previous studies have indicated that CIAPIN1 is involved in the development of multidrug resistance (MDR) in gastric cancer cells [1].

High impact information on CIAPIN1


Biological context of CIAPIN1


Anatomical context of CIAPIN1


Other interactions of CIAPIN1


Analytical, diagnostic and therapeutic context of CIAPIN1

  • To reveal the possible physiological role of CIAPIN1, we examined the expression and distribution of CIAPIN1 in fetal and adult human tissues using immunohistochemistry [1].
  • We cloned cDNA of human CIAPIN1 by RT-PCR and constructed prokaryotic expression vectors of human CIAPIN1 by inserting human CIAPIN1 coding region into pET28-a(+) and pGEX- 4T-1, respectively [4].


  1. Distribution of CIAPIN1 in normal fetal and adult human tissues. Hao, Z., Li, X., Qiao, T., Zhang, J., Shao, X., Fan, D. J. Histochem. Cytochem. (2006) [Pubmed]
  2. Subcellular Localization of CIAPIN1. Hao, Z., Li, X., Qiao, T., Du, R., Zhang, G., Fan, D. J. Histochem. Cytochem. (2006) [Pubmed]
  3. CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells. Hao, Z., Li, X., Qiao, T., Du, R., Hong, L., Fan, D. Cancer Biol. Ther. (2006) [Pubmed]
  4. Preparation and characterization of a specific monoclonal antibody against CIAPIN1. Hao, Z., Qiao, T., Jin, X., Li, X., Gao, J., Fan, D. Hybridoma (2005) (2005) [Pubmed]
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