The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

NAT14  -  N-acetyltransferase 14 (GCN5-related,...

Homo sapiens

Synonyms: K562 cell-derived leucine-zipper-like protein 1, KLP1, N-acetyltransferase 14
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on NAT14


Biological context of NAT14

  • These structural characteristics and the promoter function suggest that Klp1 may play a role in cell cycle regulation [2].
  • In order to clarify the function of Klp1, we determined the complete human Klp1 genomic structure and regulatory element in the promoter region [2].

Other interactions of NAT14

  • PF16, PF20 and KLP1 have been sequenced and their gene products localized [3].

Analytical, diagnostic and therapeutic context of NAT14

  • Gel mobility shift assays revealed that Klp1 specifically binds to CPRE [1].
  • We have performed immunological tests on isolated sunfish rod inner-outer segments (RIS-ROS) using two antibodies that recognize the conserved motor domain of numerous KIFs (anti-LAGSE, a peptide antibody, and anti-Klp1 head, generated against the N terminus of Chlamydomonas Klp1) as well as an antibody specific to a neuronal KIF, KIF3A [4].


  1. Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein. Takahashi, S., Furuyama, K., Kobayashi, A., Taketani, S., Harigae, H., Yamamoto, M., Igarashi, K., Sasaki, T., Hayashi, N. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
  2. Genomic structure and regulation of a novel human gene, Klp1. Takahashi, S., Harigae, H., Yokoyama, H., Kaku, M., Sasaki, T. Biochim. Biophys. Acta (2001) [Pubmed]
  3. The role of central apparatus components in flagellar motility and microtubule assembly. Smith, E.F., Lefebvre, P.A. Cell Motil. Cytoskeleton (1997) [Pubmed]
  4. Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors. Beech, P.L., Pagh-Roehl, K., Noda, Y., Hirokawa, N., Burnside, B., Rosenbaum, J.L. J. Cell. Sci. (1996) [Pubmed]
WikiGenes - Universities